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Non-Small Cell Lung Cancer clinical trials in Austin, TX

30 studies for Non-Small Cell Lung Cancer are looking for participants at sites in and around Austin (within about 30 miles). Open a study to see who can join and how to contact the study team.

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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • New Experimental Therapeutics - NEXT Oncology, Austin
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • NEXT Austin, Austin
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06270706

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #46, Austin
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

RecruitingPhase 3
  • Texas Oncology - South Austin, Austin
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06881784

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

RecruitingPhase 3
  • Texas Oncology- Central South., Austin
  • Texas Oncology Central South, Austin
  • Texas Oncology- Central South., Austin
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07144280

A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors

RecruitingPhase 1/2
  • Next Oncology - Austin, Austin
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07488676

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

RecruitingPhase 3
  • Clinical Study Site, Austin
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT06767514

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

RecruitingPhase 1/2
  • Texas Oncology (Balcones) - SCRI, Austin
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05267626

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

RecruitingPhase 2/3
  • Local Institution - 007-892-B, Austin
  • Local Institution - 007-892-A, Austin
  • USOR - Texas Oncology - Dallas Fort Worth (DFW) - South Austin, Austin
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT04613596

A Phase 1/1b Study of IAM1363 in HER2 Cancers

RecruitingPhase 1
  • NEXT Oncology - Austin, Austin
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • USO - Texas Oncology, Austin
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

A Study of a Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Oncology Texas, Austin
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07361562

Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Oncology - Austin, Austin
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07444814

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

RecruitingPhase 1/2
  • Texas Oncology - Central / South Texas, Austin
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT05579366

Study of XB010 in Subjects With Solid Tumors

RecruitingPhase 1
  • NEXT Austin, Austin
Ages 18 and older · All sexes · Updated Jun 22, 2026 · NCT06545331

A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types

RecruitingPhase 1
  • NEXT Texas LLC - Austin, Austin
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT07503808

A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Texas LLC - Austin, Austin
Ages 18 to 99 · All sexes · Updated Jun 16, 2026 · NCT07540572

Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's Choice of Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL Cancer

RecruitingPhase 2
  • Texas Oncology - Austin Central, Austin
Ages 18 and older · All sexes · Updated Jun 4, 2026 · NCT06463665

Phase 3 Study of Taletrectinib vs Placebo as an Adjuvant Therapy in ROS1 Positive NSCLC (TRUST-IV)

RecruitingPhase 3
  • Sarah Cannon Research Institute (SCRI) - Texas Oncology-Central South, Austin
Ages 18 and older · All sexes · Updated May 19, 2026 · NCT07154706

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

RecruitingPhase 1/2
  • University of Texas at Austin, Austin
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Oncology, Austin, TX 78758
Ages 18 and older · All sexes · Updated Apr 2, 2026 · NCT06451497

A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

RecruitingPhase 1
  • Dren Investigational Site, Austin
Ages 18 and older · All sexes · Updated Jan 7, 2026 · NCT06999187

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2
  • Research Site 135, Austin
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

A Study to Assess the Efficacy of WSD0922-FU in Patients With C797S+ Advanced Non-small Cell Lung Cancer

RecruitingPhase 2
  • TxO Central/South, Texas Oncology -Central/South Texas, Austin
Ages 18 and older · All sexes · Updated Sep 8, 2025 · NCT06868485

A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents

RecruitingPhase 1/2
  • NEXT Austin, Austin
Ages 18 and older · All sexes · Updated Jan 7, 2025 · NCT06090266

Non-Small Cell Lung Cancer trials in other cities

Other studies in Austin

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.