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Depression clinical trials in Austin, TX

15 studies for Depression are looking for participants at sites in and around Austin (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 2
  • Austin Clinical Trial Partners, Austin
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07621237

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

RecruitingPhase 2
  • Dell Medical School, University of Texas at Austin, Austin
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07002034

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)

RecruitingPhase 3
  • Austin Clinical Trial Partners, Austin
Ages 18 to 74 · All sexes · Updated Sep 8, 2026 · NCT07076407

A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression

RecruitingPhase 2
  • Draig Clinical Site, Austin
  • Draig Clinical Site, Austin
Ages 18 to 75 · All sexes · Updated Aug 26, 2026 · NCT07300969

Accelerated Intermittent Theta Burst in Treatment-Naive Adolescents

Recruiting
  • Dell Medical School at University of Texas at Austin, Austin
Ages 13 to 20 · All sexes · Updated Aug 19, 2026 · NCT06523439

Cancer Pain Management Using a Web-based Intervention

Recruiting
  • The University of Texas at Austin, Austin
Ages 18 and older · Women · Updated Jun 9, 2026 · NCT06085313

Clinical Trial on Agitation in Alzheimer's Dementia

RecruitingPhase 2
  • Senior Adults Specialty Research, Austin
Ages 60 and older · All sexes · Updated May 20, 2026 · NCT05543681

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

RecruitingPhase 2
  • Biobehavioral Research of Austin, Austin
Ages 18 to 65 · All sexes · Updated May 11, 2026 · NCT06524830

Establishing Multimodal Brain Biomarkers for Treatment Selection in Depression

RecruitingPhase 4
  • Health Discovery Building (HDB), 1601 Trinity St., Bldg B., Z0600, Austin
Ages 18 to 65 · All sexes · Updated May 1, 2026 · NCT05892744

Psilocybin rTMS for Treatment Resistant Depression

RecruitingPhase 2
  • Health Discovery Building (HDB), 1601 Trinity St., Bldg B., Z0600, Austin
Ages 22 to 65 · All sexes · Updated Nov 26, 2025 · NCT06132178

Preventing Suicide Among Sexual and Gender Diverse Young Adults in Primary Care

Recruiting
  • Steve Hicks School of Social Work at the University of Texas at Austin, Austin
Ages 18 to 24 · All sexes · Updated Nov 6, 2025 · NCT05869552

Confirmatory Efficacy Trial of Attention Bias Modification for Depression

RecruitingEarly phase 1
  • Institute for Mental Health Research, Austin
Ages 18 to 70 · All sexes · Updated Sep 15, 2025 · NCT06361095

To Improve Depressive Symptoms Using a Web-App

Recruiting
  • The University of Texas at Austin, Austin
Ages 40 to 60 · Women · Updated Sep 12, 2025 · NCT05405803

Integrated Tele-Behavioral Activation and Fall Prevention for Low-income Homebound Seniors With Depression

Recruiting
  • University of Texas at Austin, Austin
Ages 50 to 100 · All sexes · Updated Jan 9, 2024 · NCT05011864

About Depression

Depression is a serious medical illness. It affects almost 7 percent of U.S. adults. It causes feelings of sadness, hopelessness, and frustration that do not go away. Learn about treatments.

More about Depression on MedlinePlus

Depression trials in other cities

Other studies in Austin

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.