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Non-Small Cell Lung Cancer clinical trials in Charlottesville, VA

21 studies for Non-Small Cell Lung Cancer are looking for participants at sites in and around Charlottesville (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #66, Charlottesville
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Non-Small Cell Lung Cancer

RecruitingPhase 2
  • University of Virginia, Charlottesville
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07659782

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

RecruitingPhase 3
  • UVA Comprehensive Cancer Center, Charlottesville
  • UVA Health Fontaine Research Park, Charlottesville
  • University of Virginia, Charlottesville
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07222566

Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

RecruitingPhase 3
  • University of Virginia Health System, Charlottesville
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06890598

Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change

RecruitingPhase 2
  • University of Virginia Cancer Center, Charlottesville
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT03191149

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

RecruitingPhase 2/3
  • University of Virginia Health System, Charlottesville
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07100080

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

RecruitingPhase 3
  • Clinical Study Site, Charlottesville
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT06767514

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • University of Virginia Health System, Charlottesville
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

RecruitingPhase 1/2
  • University of Virginia Cancer Center, Charlottesville
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07012031

Neoadjuvant Chemo-Immunotherapy and Surgical Resection in Locally Advanced Non-small Cell Lung Cancer With N3 Lymph Node or Other High Risk Features

RecruitingPhase 2
  • UVA Comprehensive Cancer Center, Charlottesville
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06449313

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

RecruitingPhase 2
  • University of Virginia Cancer Center, Charlottesville
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05642572

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2
  • University of Virginia Cancer Center, Charlottesville
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06116682

Adjuvant Pembrolizumab vs Observation Following Curative Resection for Stage I Non-small Cell Lung Cancer (NSCLC) With Primary Tumors Between 1-4 cm

RecruitingPhase 2
  • University of Virginia Health System, Charlottesville
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT04317534

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

RecruitingPhase 1/2
  • University of Virginia, Charlottesville
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT07020221

Adagrasib + SRS for Patients With Metastatic KRAS G12C-mutated NSCLC With Untreated Brain Metastases

RecruitingPhase 2
  • University of Virginia Health System, Charlottesville
Ages 18 and older · All sexes · Updated Apr 8, 2026 · NCT06248606

GEMINI-NSCLC: NSCLC Biomarker Study

RecruitingObservational study
  • University of Virginia, Charlottesville
Ages 18 and older · All sexes · Updated Feb 5, 2026 · NCT05236114

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Charlottesville
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study of NX-1607 in Adults With Advanced Malignancies

RecruitingPhase 1
  • University of Virginia, Charlottesville
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT05107674

Non-Small Cell Lung Cancer trials in other cities

Other studies in Charlottesville

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.