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Ovarian Cancer clinical trials in Oklahoma City, OK

28 studies for Ovarian Cancer are looking for participants at sites in and around Oklahoma City (within about 30 miles). Open a study to see who can join and how to contact the study team.

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The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • University of Oklahoma Health Sciences Center, Oklahoma City
Ages 45 to 75 · All sexes · Updated Oct 5, 2026 · NCT06995898

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

RecruitingPhase 2
  • University of Oklahoma Health Sciences Center, Oklahoma City
All ages · All sexes · Updated Oct 5, 2026 · NCT05564377

Phase II IMNN-001 (Also Known as GEN-1) on SLL With BEV and NACT, Newly Diagnosed Advanced Ovarian, Fallopian Tube or Primary Peritoneal Cancer

RecruitingPhase 1/2
  • OU Health, Stephenson Cancer Center, Oklahoma City
Ages 18 and older · Women · Updated Oct 5, 2026 · NCT05739981

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • University of Oklahoma, Oklahoma City
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

A Study to Assess Change in Disease Activity and Adverse Events in Adult Participants With Gynecologic Cancers Receiving Intravenous Infusion of IMGN151 as Monotherapy or in Combination With Other Therapies

RecruitingPhase 2
  • OU Health - Stephenson Cancer Center /ID# 277656, Oklahoma City
Ages 18 and older · Women · Updated Oct 1, 2026 · NCT07024784

Study of AVZO-021 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Avenzo Therapeutics Recruiting Site, Oklahoma City
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05867251

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

RecruitingPhase 3
  • University of Oklahoma Health Sciences Center, Stephenson Cancer Center, Oklahoma City
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213804

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • University of Oklahoma, Oklahoma City
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC

RecruitingPhase 1/2
  • OU Health Stephenson Cancer Center, Oklahoma City
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06303505

Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

RecruitingPhase 3
  • Oklahoma University Health Stephenson Cancer Center, Oklahoma City
Ages 18 and older · Women · Updated Aug 26, 2026 · NCT05281471

Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors

RecruitingPhase 1
  • OU Health Stephenson Cancer Center, Oklahoma City
Ages 15 and older · All sexes · Updated Aug 25, 2026 · NCT06276491

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

RecruitingPhase 1
  • Normunity Investigational Site, Oklahoma City
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07182149

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Recruiting
  • University of Oklahoma Health Sciences Center, Oklahoma City
  • Mercy Hospital Oklahoma City, Oklahoma City
Ages 35 to 50 · Women · Updated Aug 7, 2026 · NCT04251052

A Study of DM002 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • University of Oklahoma Health Sciences Center, Oklahoma City
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06751329

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

RecruitingPhase 3
  • University of Oklahoma Health Sciences Center, Oklahoma City
  • Mercy Hospital Oklahoma City, Oklahoma City
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06580314

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

RecruitingPhase 1/2
  • University of Oklahoma - Health Sciences Center, Oklahoma City
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT05579366

Clinical Pre-screening Protocol for Ovarian Cancer

RecruitingObservational study
  • OU Health Stephenson Cancer Center, Oklahoma City
Ages 18 and older · Women · Updated Jul 30, 2026 · NCT03877796

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Stephenson Cancer Center, Oklahoma City
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04657068

A Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

RecruitingPhase 2/3
  • University of Oklahoma Health Sciences Center, Oklahoma City
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT06161025

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

RecruitingPhase 1
  • OU Health University of Oklahoma Medical Center, Oklahoma City
  • Stephenson Cancer Center (chemo location), Oklahoma City
  • University of Oklahoma Health Science Center, Oklahoma City
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT04389632

A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors

RecruitingPhase 1/2
  • Stephenson Cancer Center Oklahoma University Health, Oklahoma City
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05377996

Use of CA125 and Complementary Biomarkers for the Early Detection of Ovarian Cancer in Low Risk Women

RecruitingHealthy volunteers welcome
  • University of Oklahoma Health Sciences Center, Oklahoma City
Ages 50 to 74 · Women · Updated May 6, 2026 · NCT00539162

A Study of CUSP06 in Patients With Platinum-Refractory/Resistant Ovarian Cancer and Other Advanced Solid Tumors

RecruitingPhase 1
  • Stephenson Cancer Center, Oklahoma City
Ages 18 and older · All sexes · Updated Jan 14, 2026 · NCT06234423

A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

RecruitingPhase 1
  • Dren Investigational Site, Oklahoma City
Ages 18 and older · All sexes · Updated Jan 7, 2026 · NCT06999187

CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.

RecruitingPhase 2
  • Stephenson Cancer Center at the University of Oklahoma, Oklahoma City
Ages 18 and older · Women · Updated Dec 23, 2025 · NCT06690775

A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #13, Oklahoma City
Ages 18 and older · All sexes · Updated Sep 5, 2025 · NCT05932862

About Ovarian Cancer

Ovarian cancer is a cancerous tumor that forms in the tissues of an ovary. The ovaries are a pair of female reproductive glands that make eggs and female hormones.

More about Ovarian Cancer on MedlinePlus

Ovarian Cancer trials in other cities

Other studies in Oklahoma City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.