🔎 Trials Near Me

Home › Ovarian Cancer › Ohio › Columbus

Ovarian Cancer clinical trials in Columbus, OH

39 studies for Ovarian Cancer are looking for participants at sites in and around Columbus (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

RecruitingPhase 2
  • Ohio State University Comprehensive Cancer Center, Columbus
  • Mount Carmel East Hospital, Columbus
  • Columbus Oncology and Hematology Associates Inc, Columbus
  • and 13 more
All ages · All sexes · Updated Oct 2, 2026 · NCT05564377

A Study of Azenosertib (ZN-c3) in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer

RecruitingPhase 2
  • Site 0243 - Mark H Zangmeister Cancer Center, Columbus
  • Site 0214-Ohio State University Comprehensive Cancer Center, Hilliard · 10 mi away
Ages 18 and older · Women · Updated Sep 29, 2026 · NCT05128825

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

RecruitingObservational study
  • The Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04981119

Study of REGN4018 (Ubamatamab) Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers

RecruitingPhase 1/2
  • The Ohio State University Wexner Medical Center, Columbus
Ages 18 and older · Women · Updated Sep 25, 2026 · NCT03564340

A Study to Find Out How Safe REGN5668 is and How Well it Works In Adult Women When Given With Either Cemiplimab, or Cemiplimab + Fianlimab, or Ubamatamab

RecruitingPhase 1/2
  • The Ohio State University Wexner Medical Center, Columbus
Ages 18 and older · Women · Updated Sep 24, 2026 · NCT04590326

Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

RecruitingPhase 2
  • Research Site, Columbus
Ages 18 to 130 · All sexes · Updated Sep 23, 2026 · NCT05489211

A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer

RecruitingPhase 2
  • Jamescare Gynecologic Oncology At Mill Run /ID# 277951, Hilliard · 10 mi away
Ages 18 and older · Women · Updated Sep 22, 2026 · NCT07059845

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

RecruitingPhase 3
  • The Mark H Zangmeister Center, Columbus
  • The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer -T, Hilliard · 10 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213804

A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

RecruitingPhase 2
  • The Mark H Zangmeister Cancer Center Ohio, Columbus
  • The Ohio State University Wexner Medical Center Division of Gynecologic Oncology, Hilliard · 10 mi away
Ages 18 to 99 · Women · Updated Sep 15, 2026 · NCT07023627

Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

RecruitingPhase 3
  • Ohio Health Research Institute, Columbus
Ages 18 and older · Women · Updated Sep 15, 2026 · NCT07214779

FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC

RecruitingPhase 1/2
  • Ohio State University, Columbus
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06303505

Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

RecruitingPhase 2
  • The Ohio State University Comprehensive Cancer Center, Hilliard · 10 mi away
Ages 18 and older · Women · Updated Sep 14, 2026 · NCT06787612

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

RecruitingPhase 1
  • The Ohio State University (OSU) Wexner Medical Center, Columbus
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06400472

A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

RecruitingPhase 3
  • The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C ( Site 0054), Columbus
Ages 18 and older · Women · Updated Sep 3, 2026 · NCT06824467

Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors

RecruitingPhase 1
  • The Ohio State University, Columbus
Ages 15 and older · All sexes · Updated Aug 25, 2026 · NCT06276491

Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

RecruitingPhase 1/2
  • Research Site, Columbus
Ages 18 to 130 · All sexes · Updated Aug 21, 2026 · NCT05797168

Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity

RecruitingPhase 2/3
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07001748

A Study of MUC16-Directed Antibody Drug Conjugate HWK-016 in Participants With Advanced Solid Tumors.

RecruitingPhase 1
  • Ohio State University Wexner Medical Center, Columbus
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07470853

Effects of a Probiotic Intervention on the Gut and Vaginal Microbiome in Patients With Advanced or Recurrent Ovarian Cancer Undergoing Treatment With Platinum Chemotherapy

RecruitingEarly phase 1
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · Women · Updated Aug 17, 2026 · NCT07144826

Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • The Ohio State University, Columbus
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT05985655

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Recruiting
  • Ohio State University Comprehensive Cancer Center, Columbus
  • Columbus Oncology and Hematology Associates Inc, Columbus
  • Riverside Methodist Hospital, Columbus
  • and 8 more
Ages 35 to 50 · Women · Updated Aug 7, 2026 · NCT04251052

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

RecruitingPhase 3
  • Ohio State University Comprehensive Cancer Center, Columbus
  • Columbus Oncology and Hematology Associates Inc, Columbus
  • Riverside Methodist Hospital, Columbus
  • and 8 more
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06580314

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

RecruitingPhase 1/2
  • Ohio State University Comprehensive Cancer Center (OSUCCC)- The James Cancer Hospital and Solove Research Institute, Columbus
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT05579366

A Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

RecruitingPhase 2/3
  • Ohio State University Wexner Medical Center, Hilliard · 10 mi away
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT06161025

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

RecruitingPhase 2
  • The Ohio State University Comprehensive Cancer Center (OSUCCC) - The James Cancer Hospital and Solove Research Institute, Columbus
Ages 8 and older · All sexes · Updated Jul 27, 2026 · NCT05503797

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Stefanie Spielman Comprehensive Breast Center, Columbus
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT05768139

Lead-212 PSV359 Therapy for Patients With Solid Tumors

RecruitingPhase 1/2
  • Ohio State University, Columbus
Ages 18 to 90 · All sexes · Updated Jul 6, 2026 · NCT06710756

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • The Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation

RecruitingPhase 1
  • Ohio State University-James Cancer Hospital and Solove Research Institute, Columbus
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT04890613

ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors

RecruitingPhase 1/2
  • Ohio State University Wexner Medical Center Gynecologic Oncology at Mill Run, Columbus
Ages 18 and older · All sexes · Updated May 13, 2026 · NCT03686124

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

RecruitingPhase 1/2
  • Stefanie Spielman Comprehensive Breast Center, Columbus
Ages 18 and older · All sexes · Updated Mar 27, 2026 · NCT06395519

CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.

RecruitingPhase 2
  • The James Cancer Hospital and Solove Research Institute - Ohio State University, Columbus
Ages 18 and older · Women · Updated Dec 23, 2025 · NCT06690775

A Study of MT-4561 in Patients With Various Advanced Solid Tumors

RecruitingPhase 1/2
  • The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Dec 11, 2025 · NCT06943521

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Columbus
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

About Ovarian Cancer

Ovarian cancer is a cancerous tumor that forms in the tissues of an ovary. The ovaries are a pair of female reproductive glands that make eggs and female hormones.

More about Ovarian Cancer on MedlinePlus

Ovarian Cancer trials in other cities

Other studies in Columbus

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.