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Prostate Cancer clinical trials in Oklahoma City, OK

21 studies for Prostate Cancer are looking for participants at sites in and around Oklahoma City (within about 30 miles). Open a study to see who can join and how to contact the study team.

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

RecruitingPhase 2
  • University of Oklahoma Health Sciences Center, Oklahoma City
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

Hypo-fractionated Radiation Therapy With or Without Androgen Suppression for Intermediate Risk Prostate Cancer

RecruitingPhase 3
  • Oklahoma Proton Center, Oklahoma City
Ages 18 and older · Men · Updated Sep 29, 2026 · NCT01492972

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

RecruitingPhase 3
  • Hightower Clinical, Oklahoma City
Ages 18 and older · Men · Updated Sep 22, 2026 · NCT07213674

Protoacoustic Imaging For 3D Mapping

RecruitingObservational study
  • OU Health Stephenson Cancer Center, Oklahoma City
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07832617

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • University of Oklahoma, Oklahoma City
Ages 12 and older · All sexes · Updated Sep 15, 2026 · NCT04585750

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

RecruitingPhase 3
  • University of Oklahoma Health Sciences Center, Oklahoma City
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05946213

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

RecruitingPhase 3
  • University of Oklahoma Health Sciences Center, Oklahoma City
Ages 18 and older · Men · Updated Sep 2, 2026 · NCT06931340

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • University of Oklahoma Health Sciences Center, Oklahoma City
Ages 45 to 75 · All sexes · Updated Sep 2, 2026 · NCT06995898

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Mercy Hospital Oklahoma City, Oklahoma City
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

RecruitingPhase 2
  • University of Oklahoma Health Sciences Center, Oklahoma City
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06632977

Characterizing the Genomic Landscape of Prostate Cancer in Native American Populations (NAT-Geno)

RecruitingObservational study
  • OU Health Stephenson Cancer Center, Oklahoma City
Ages 18 to 100 · Men · Updated Aug 26, 2026 · NCT06960798

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

RecruitingPhase 3
  • University of Oklahoma Health Sciences Center, Oklahoma City
  • Mercy Hospital Oklahoma City, Oklahoma City
Ages 18 and older · Men · Updated Aug 19, 2026 · NCT04423211

A Study of DM002 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • University of Oklahoma Health Sciences Center, Oklahoma City
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06751329

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

RecruitingPhase 3
  • University of Oklahoma Health Sciences Center, Oklahoma City
Ages 18 and older · Men · Updated Jul 14, 2026 · NCT06592924

Using a mHealth App to Improve Quality-of-Life Outcomes in Black Prostate Cancer Survivors

Recruiting
  • University of Oklahoma HSC, Oklahoma City
Ages 18 and older · Men · Updated Apr 1, 2026 · NCT06651359

Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

RecruitingPhase 2
  • University of Oklahoma Health Sciences Center, Oklahoma City
Ages 18 and older · Men · Updated Jan 29, 2026 · NCT05806515

Navigator-Assisted Hypofractionation (NAVAH) on Radiation Therapy Completion in Breast Cancer and Prostate Cancer

RecruitingObservational study
  • OU Health Stephenson Cancer Center, Oklahoma City
Ages 18 and older · All sexes · Updated Dec 17, 2025 · NCT07014618

Connect2Care: Prostate Cancer Education and Screenings for African American Men

Recruiting
  • TSET Health Promotion Research Center, Oklahoma City
Ages 45 to 69 · Men · Updated Sep 25, 2025 · NCT07055165

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

RecruitingPhase 3
  • University of Oklahoma Health Sciences Center, Oklahoma City
Ages 18 and older · Men · Updated Sep 11, 2025 · NCT03678025

A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #13, Oklahoma City
Ages 18 and older · All sexes · Updated Sep 5, 2025 · NCT05932862

About Prostate Cancer

Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.

More about Prostate Cancer on MedlinePlus

Prostate Cancer trials in other cities

Other studies in Oklahoma City

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.