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Steatotic Liver Disease clinical trials in Houston, TX

13 studies for Steatotic Liver Disease are looking for participants at sites in and around Houston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

RecruitingPhase 3
  • 89bio Clinical Study Site, Houston
  • 89bio Clinical Study Site, Houston
  • 89bio Clinical Study Site, Houston
Ages 18 to 75 · All sexes · Updated Oct 5, 2026 · NCT06419374

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

RecruitingPhase 3
  • 89bio Clinical Study Site, Houston
  • 89bio Clinical Study Site, Houston
  • 89bio Clinical Study Site, Houston
  • and 1 more
Ages 18 to 80 · All sexes · Updated Oct 5, 2026 · NCT06318169

A Study to Investigate Safety and Efficacy of Efimosfermin Compared With Placebo in Adult Participants With Compensated Cirrhosis Due to Metabolic Dysfunction-associated Steatohepatitis (MASH)

RecruitingPhase 3
  • GSK Investigational Site, Houston
  • GSK Investigational Site, Bellaire · 7 mi away
  • GSK Investigational Site, Humble · 17 mi away
Ages 18 to 75 · All sexes · Updated Sep 30, 2026 · NCT07704892

A Pivotal Clinical Study to Investigate the Safety and Efficacy of Efimosfermin Compared With Placebo in Adult Participants With Compensated Cirrhosis Due to Metabolic Dysfunction-associated Steatohepatitis (MASH)

RecruitingPhase 3
  • GSK Investigational Site, Bellaire · 7 mi away
  • GSK Investigational Site, Humble · 17 mi away
Ages 18 to 75 · All sexes · Updated Sep 30, 2026 · NCT07701993

A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

RecruitingPhase 3
  • HRI- Medical Center, Houston
  • Care Access - Houston, Houston
  • Houston Research Institute, Houston
  • and 3 more
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07165028

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

RecruitingPhase 3
  • Akero Clinical Study Site, Houston
  • Akero Clinical Study Site, Houston
  • Akero Clinical Study Site, Houston
  • and 3 more
Ages 18 to 80 · All sexes · Updated Sep 21, 2026 · NCT06528314

A Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH)

RecruitingPhase 2
  • Houston Research Institute - Medical Center, Houston
  • Houston Research Institute, Houston
  • Bellaire Clinical Research, Bellaire · 7 mi away
Ages 18 to 75 · All sexes · Updated Sep 9, 2026 · NCT07288138

A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH

RecruitingPhase 3
  • GSK Investigational Site, Houston
  • GSK Investigational Site, Bellaire · 7 mi away
Ages 18 to 75 · All sexes · Updated Jul 27, 2026 · NCT07221227

A Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH

RecruitingPhase 2
  • GSK Investigational Site, Houston
  • GSK Investigational Site, Houston
  • GSK Investigational Site, Houston
Ages 18 to 75 · All sexes · Updated Jul 8, 2026 · NCT06920043

A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

RecruitingPhase 1/2Healthy volunteers welcome
  • Pioneer Research Solutions, Houston
Ages 18 to 75 · All sexes · Updated Apr 16, 2026 · NCT05648214

NAFLD Clinical Care Pathway

RecruitingHealthy volunteers welcome
  • Michael E. DeBakey VA Medical Center, Houston, TX, Houston
Ages 18 and older · All sexes · Updated Nov 14, 2025 · NCT06671886

Evaluation of Non-Invasive Tests for Metabolic Liver Disease

RecruitingObservational study
  • First Surgical Hospital, Bellaire · 7 mi away
Ages 18 to 75 · All sexes · Updated Aug 14, 2025 · NCT07122700

About Steatotic Liver Disease

Steatotic liver disease, formerly called fatty liver disease, happens when too much fat builds up in your liver. Learn about the causes and treatments.

More about Steatotic Liver Disease on MedlinePlus

Steatotic Liver Disease trials in other cities

Other studies in Houston

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.