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Healthy volunteer studies in Cambridge, MA

23 studies at sites in and around Cambridge accept healthy volunteers — people without the condition being studied. Many studies pay participants for their time and travel; the amount is set by each study, so ask the study team.

Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older

RecruitingPhase 1/2Healthy volunteers welcome
  • DM Clinical Research - Brookline- Site Number : 8400055, Brookline · 3 mi away
Ages 60 and older · All sexes · Updated Sep 24, 2026 · NCT07734649

A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age

RecruitingPhase 3Healthy volunteers welcome
  • GSK Investigational Site, Brookline · 3 mi away
Ages 65 and older · All sexes · Updated Sep 18, 2026 · NCT07805707

Recovery Inspired Support Engagement (RISE) Pilot

RecruitingHealthy volunteers welcome
  • McLean Hospital, Belmont · 4 mi away
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07519759

AMI Construction in Lower Extremity Residual Limbs

RecruitingHealthy volunteers welcome
  • Massachusetts Institute of Technology, Cambridge
Ages 18 to 65 · All sexes · Updated Jul 9, 2026 · NCT04063592

A Novel Approach to Upper Extremity Amputation to Augment Volitional Control and Restore Proprioception

RecruitingHealthy volunteers welcome
  • Massachusetts Institute of Technology Media Lab, Cambridge
Ages 18 to 65 · All sexes · Updated Jul 9, 2026 · NCT03882073

fMRI in CardiaC arrEst With Uncertain Prognosis

RecruitingObservational studyHealthy volunteers welcome
  • Brigham and Women's Hospital, Brookline · 3 mi away
Ages 18 and older · All sexes · Updated Jun 22, 2026 · NCT06423768

Gamma Light and Sound Stimulation to Prevent Dementia in Cognitively Normal People at Risk for Alzheimer's Disease

RecruitingHealthy volunteers welcome
  • Massachusetts Institute of Technology, Cambridge
Ages 55 to 90 · All sexes · Updated Jun 18, 2026 · NCT05776641

Study of Wearable Interventions for Improving Mobility of Individuals With Knee Osteoarthritis

RecruitingHealthy volunteers welcome
  • MIT Media Lab, Cambridge
Ages 21 to 100 · All sexes · Updated Jun 17, 2026 · NCT07652437

Mechanisms and Predictors of Change in App-Based Mindfulness Training for Adolescents

RecruitingHealthy volunteers welcome
  • McLean Hospital, Belmont · 4 mi away
Ages 13 to 18 · All sexes · Updated Jun 17, 2026 · NCT04697966

Evaluation of a Powered Ankle Prosthesis Capable of Bidirectional Control Via Neural Recording and Cutaneous Stimulation in Free-Space and Walking Tasks

RecruitingHealthy volunteers welcome
  • MIT Media Lab, Cambridge
Ages 18 to 70 · All sexes · Updated Jun 12, 2026 · NCT07645729

Neural Correlates of Stress and Perceived Control in Adolescent Depression

RecruitingHealthy volunteers welcome
  • McLean Hospital, Belmont · 4 mi away
Ages 14 to 18 · Women · Updated May 19, 2026 · NCT04788524

Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Pharmacological Manipulation

RecruitingPhase 2Healthy volunteers welcome
  • Mclean Hospital, Belmont · 4 mi away
Ages 18 to 45 · All sexes · Updated May 18, 2026 · NCT05232032

Use of Ketosis in Modulating Metabolic Pathways in Bipolar Disorder

RecruitingHealthy volunteers welcome
  • McLean Hospital, Belmont · 4 mi away
Ages 18 to 45 · All sexes · Updated Apr 15, 2026 · NCT06373016

Gamma Frequency Stimulation in Individuals With Down Syndrome

RecruitingHealthy volunteers welcome
  • Massachusetts Institute of Technology, Cambridge
Ages 25 to 65 · All sexes · Updated Mar 31, 2026 · NCT05196984

Chronic Treatment of Alzheimer's Disease by Gamma Light and Sound Therapy

RecruitingHealthy volunteers welcome
  • Massachusetts Institute of Technology, Cambridge
Ages 65 to 100 · All sexes · Updated Mar 30, 2026 · NCT05655195

Brain Effects of Gamma Frequency Sensory Stimulation (40Hz Light, Sound and Other Devices)

RecruitingPhase 2Healthy volunteers welcome
  • MIT, Cambridge
Ages 18 to 100 · All sexes · Updated Mar 27, 2026 · NCT07496918

Effects of Breathing Mild Bouts of Low Oxygen on Limb Mobility After Spinal Injury

RecruitingHealthy volunteers welcome
  • Spaulding Rehabilitation Hospital, Cambridge
Ages 18 to 75 · All sexes · Updated Mar 20, 2026 · NCT02323945

Early Life Stress and Depression: Molecular and Functional Imaging

RecruitingObservational studyHealthy volunteers welcome
  • McLean Hospital, Belmont · 4 mi away
Ages 20 to 32 · Women · Updated Dec 12, 2025 · NCT04713722

Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans

RecruitingHealthy volunteers welcome
  • McLean Hospital, Belmont · 4 mi away
Ages 18 to 65 · All sexes · Updated Dec 5, 2025 · NCT06105164

Evaluating Q-Collar Effects on Brain Blood Flow Control During Exercise

RecruitingHealthy volunteers welcome
  • Spaulding Rehabilitation Hospital, Cambridge
Ages 18 to 30 · All sexes · Updated Oct 27, 2025 · NCT06826781

Stress Dynamics and Familial Risk for Depression in Female Adolescents

RecruitingHealthy volunteers welcome
  • McLean Hospital, Belmont · 4 mi away
Ages 13 to 15 · Women · Updated Oct 23, 2025 · NCT06816329

Beyond Monoamines: The Role of the Nociceptin/Orphanin FQ Receptor in Major Depression

RecruitingObservational studyHealthy volunteers welcome
  • McLean Hospital, Belmont · 4 mi away
Ages 18 to 45 · All sexes · Updated Oct 21, 2025 · NCT05630963

Neurophysiologic Biomarkers in Rett Syndrome

RecruitingObservational studyHealthy volunteers welcome
  • Boston Children's Hospital, Brookline · 3 mi away
Ages 1 to 18 · Women · Updated Oct 20, 2025 · NCT05932589

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.