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Prostate Cancer clinical trials in Virginia

54 studies for Prostate Cancer are looking for participants at sites in Virginia.

Cities in Virginia

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

  • Virginia Cancer Specialists, Fairfax
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

  • Hematology Oncology Associates of Fredericksburg Inc, Fredericksburg
  • VCU Massey Cancer Center at Stony Point, Richmond
  • VCU Massey Comprehensive Cancer Center, Richmond
  • and 1 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Oct 2, 2026 · NCT06931340

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • Chesapeake Regional Medical Center, Chesapeake
  • Augusta Health Center for Cancer and Blood Disorders, Fishersville
  • Bon Secours Memorial Regional Medical Center, Mechanicsville
  • and 7 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

  • Bon Secours Memorial Regional Medical Center, Mechanicsville
  • Bon Secours Saint Francis Medical Center, Midlothian
  • Bon Secours Richmond Community Hospital, Richmond
  • and 4 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06632977

Autonomic and Renal Contributions to Hypertension With ADT

  • Virginia Commonwealth University, Richmond
RecruitingPhase 4Healthy volunteers welcome
Ages 40 and older · Men · Updated Sep 30, 2026 · NCT07848828

Hypo-fractionated Radiation Therapy With or Without Androgen Suppression for Intermediate Risk Prostate Cancer

  • Hampton University Proton Therapy Institute, Hampton
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 29, 2026 · NCT01492972

Barrigel® PPRT (Post-Prostatectomy Radiation Therapy) Trial

  • Virginia Urology Center, Richmond
Recruiting
Ages 18 and older · Men · Updated Sep 28, 2026 · NCT06496256

Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer

  • Virginia Clinical Research, Norfolk
RecruitingPhase 1/2
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06800313

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

  • University of Virginia Health System ( Site 0054), Charlottesville
  • Inova Schar Cancer Institute ( Site 0017), Fairfax
  • Virginia Cancer Specialists (VCS) ( Site 8004), Fairfax
  • and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06136650

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

  • Blue Ridge Cancer Care, Blacksburg
  • University of Virginia Comprehensive Cancer Center, Charlottesville
  • University of Virginia, Charlottesville
  • and 5 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 24, 2026 · NCT07028853

Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy

  • Virginia Cancer Specialists, Fairfax
  • Onco Hemato Asso of SW Virginia, Roanoke
RecruitingPhase 2/3
Ages 18 to 100 · Men · Updated Sep 22, 2026 · NCT06780670

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

  • University of Virginia Cancer Center, Charlottesville
  • Virginia Cancer Specialists PC, Leesburg
  • Bon Secours Cancer Institute at Saint Francis, Midlothian
  • and 1 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 22, 2026 · NCT07213674

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

  • Research Site, Norfolk
  • Research Site, Roanoke
  • Research Site, Virginia Beach
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 18, 2026 · NCT06952803

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

  • Blue Ridge Cancer Care ( Site 0024), Roanoke
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT06925737

Trial of Xaluritamig in Adults With Metastatic Castration-resistant Prostate Cancer

  • Virginia Oncology Associates - Hampton, Norfolk
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 15, 2026 · NCT07493512

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

  • Potomac Urology, Woodbridge
Recruiting
Ages 18 and older · Men · Updated Sep 14, 2026 · NCT06511141

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

  • Augusta Health Center for Cancer and Blood Disorders, Fishersville
  • Bon Secours Memorial Regional Medical Center, Mechanicsville
  • VCU Massey Cancer Center at Hanover Medical Park, Mechanicsville
  • and 5 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05946213

Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer

  • Investigational Site number: 404, Fairfax
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05997615

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

  • NEXT Oncology, Fairfax
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06440005

A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

  • University of Virginia Cancer Center, Charlottesville
RecruitingPhase 2
Ages 18 and older · Men · Updated Sep 3, 2026 · NCT07005154

Prostate Active Surveillance Study

  • Eastern Virginia Medical School, Norfolk
RecruitingObservational study
Ages 21 and older · Men · Updated Sep 2, 2026 · NCT00756665

The Vanguard Study: Testing a New Way to Screen for Cancer

  • Sentara Martha Jefferson Hospital, Charlottesville
  • Inova Schar Cancer Institute, Fairfax
  • Inova Fair Oaks Hospital, Fairfax
  • and 5 more
RecruitingHealthy volunteers welcome
Ages 45 to 75 · All sexes · Updated Sep 2, 2026 · NCT06995898

Study of Oral MRT-2359 With Apalutamide in Prostate Cancer

  • Virginia Cancer Specialists, Fairfax
RecruitingPhase 2
Ages 18 and older · Men · Updated Aug 24, 2026 · NCT07745361

Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

  • Virginia Cancer Specialists PC, Fairfax
RecruitingPhase 1
Ages 18 and older · Men · Updated Aug 21, 2026 · NCT04221542

A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC

  • NEXT Oncology - Virginia, Fairfax
RecruitingPhase 1/2
Ages 18 and older · Men · Updated Aug 20, 2026 · NCT06785636

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

  • University of Virginia Cancer Center, Charlottesville
  • VCU Massey Comprehensive Cancer Center, Richmond
RecruitingPhase 3
Ages 18 and older · Men · Updated Aug 19, 2026 · NCT04423211

Water Vapor Ablation for Prostate Cancer: Long-Term Registry

  • Urology of Virginia, Virginia Beach
RecruitingObservational study
All ages · Men · Updated Aug 18, 2026 · NCT07455058

A Study of FG-3246 in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

  • University of Virginia Comprehensive Cancer Center, Charlottesville
RecruitingPhase 2
Ages 18 and older · Men · Updated Aug 17, 2026 · NCT06842498

FOG-001 in Locally Advanced or Metastatic Solid Tumors

  • University of Virginia, Charlottesville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

PSMA PET Combined With MRI for the Detection of PCa

  • Urology of Virginia, Virginia Beach
RecruitingPhase 3Healthy volunteers welcome
Ages 18 and older · Men · Updated Jul 23, 2026 · NCT07052214

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

  • University of Virginia Cancer Center, Charlottesville
  • Bon Secours Memorial Regional Medical Center, Mechanicsville
  • Bon Secours Saint Francis Medical Center, Midlothian
  • and 3 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Jul 14, 2026 · NCT06592924

Study of ORIC-944 in Patients With Metastatic Prostate Cancer

  • Virginia Oncology Associates, Fairfax
  • Virginia Cancer Specialists, Norfolk
RecruitingPhase 1
Ages 18 and older · Men · Updated Jul 9, 2026 · NCT05413421

Postoperative or Salvage Radiotherapy (RT) for Node Negative Prostate Cancer Following Radical Prostatectomy

  • Inova Schar Cancer Institute, Fairfax
Recruiting
Ages 18 and older · Men · Updated Jun 17, 2026 · NCT00969111

HER2 FPBMC in Patients With Metastatic Breast and Prostate Cancer (AM006)

  • University of Virginia, Charlottesville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07441889

Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer

  • Onco Hemato Asso of SW Virginia, Roanoke
RecruitingPhase 4
Ages 18 to 100 · Men · Updated Jun 4, 2026 · NCT05803941

TERPS Trial for de Novo Oligometastic Prostate Cancer

  • Bon Secours Cancer Institute at St. Francis, Midlothian
RecruitingPhase 2
Ages 18 and older · Men · Updated Jun 3, 2026 · NCT05223803

International Registry for Men With Advanced Prostate Cancer (IRONMAN)

  • University of Virginia, Charlottesville
RecruitingObservational study
Ages 21 and older · Men · Updated May 22, 2026 · NCT03151629

Remotely Monitored Exercise Interventions in Patients With mCSPC Undergoing ADT (Prostate 006)

  • University of Virginia, Charlottesville
Recruiting
Ages 18 and older · Men · Updated May 4, 2026 · NCT06429813

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.