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Cancer (all types) clinical trials in California
175 studies for Cancer (all types) are looking for participants at sites in California.
Cities in California
- Los Angeles73 studies
- Mountain View40 studies
- San Francisco35 studies
- Baldwin Park33 studies
- San Diego32 studies
- Santa Monica21 studies
- Irvine16 studies
- Orange13 studies
- Santa Rosa11 studies
- Sacramento11 studies
- Santa Barbara7 studies
- Concord7 studies
- Huntington Beach6 studies
- Newport Beach6 studies
- San Jose6 studies
- Long Beach6 studies
- Fullerton5 studies
- Glendale5 studies
- Vallejo5 studies
- Oakland5 studies
- Roseville4 studies
- Richmond4 studies
- Fresno4 studies
- Mission Viejo3 studies
- Sunnyvale3 studies
- Modesto3 studies
- Bakersfield3 studies
- Santa Clara3 studies
- Pleasanton3 studies
A Study of Mocertatug Rezetecan in Combination With Anti-cancer Therapies for Advanced Solid Tumors (BEHOLD-2)
- GSK Investigational Site, La Jolla
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06796907Distance-Based Exercise to Preserve Function and Prevent Disability
- Kaiser Permanente Dublin, Dublin
- Kaiser Permanente-Fremont, Fremont
- Kaiser Permanente Fresno Orchard Plaza, Fresno
- and 10 more
Recruiting
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07059884Phase 1/2 Study of BHB810 in Advanced Gastric and GEJ Adenocarcinoma
- City of Hope Duarte, Duarte
- University of California at Los Angeles, Santa Monica
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07529808A Study to Assess Change in Disease Activity and Adverse Events in Adult Participants With Gynecologic Cancers Receiving Intravenous Infusion of IMGN151 as Monotherapy or in Combination With Other Therapies
- Start Los Angeles /ID# 281533, Los Angeles
RecruitingPhase 2
Ages 18 and older · Women · Updated Oct 1, 2026 · NCT07024784A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan, Monotherapy or in Combination With Osimertinib, Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer
- City of Hope National Medical Center /ID# 277005, Duarte
- City of Hope - Orange County Lennar Foundation Cancer Center /ID# 277928, Irvine
- UC San Diego Health - Moores Cancer Center /ID# 278836, La Jolla
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07155187A Study of ASP3082 in Adults With Advanced Solid Tumors
- City of Hope National Medical Center, Duarte
- UCLA Santa Monica Hematology Oncology, Santa Monica
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT05382559A First-in-Human Study of KK2223 in Participants With Relapsed or Refractory T Cell Non-Hodgkin Lymphoma
- City of Hope, Duarte
- University of California, Irvine Medical Center - Hematology/Oncology, Orange
- Stanford University School of Medicine, Stanford
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07192471Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)
- Samsun Clinic - Ridley-Tree Cancer Center, Santa Barbara
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07566156A Study to Evaluate Adverse Events, Change in Disease Activity, Tolerability, and How Intravenous ABBV-438 Moves Through the Body in Adult Participants With Multiple Myeloma (MM)
- City of Hope National Medical Center /ID# 280273, Duarte
- City of Hope - Orange County Lennar Foundation Cancer Center /ID# 279067, Irvine
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07409246A Study to Assess Adverse Events, Change in Disease Activity and Optimal Dose of Intravenous (IV) Telisotuzumab Adizutecan With IV Pembrolizumab for First-Line Treatment of Adult Participants With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
- City Of Hope Comprehensive Cancer Center /ID# 281939, Duarte
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07744126uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto
- Providence St. Johns Health Center, Santa Monica
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05874921Registry Study for Radiation Therapy Outcomes
- California Protons Cancer Therapy Center, San Diego
RecruitingObservational study
All ages · All sexes · Updated Sep 29, 2026 · NCT01255748A Study of PHN-012 in Patients With Advanced Solid Tumors
- PHN-012-001 Site, Los Angeles
- PHN-012-001 Site, San Diego
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07127874A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Clinical Activity of RO7673396 in Participants With Advanced Solid Tumors Harboring Rat Sarcoma Viral Oncogene Homolog (RAS) Mutation(s)
- City of Hope Comprehensive Cancer Center, Duarte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06884618A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
- Sansum Clinic, Santa Barbara
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Sep 25, 2026 · NCT05920356Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
- University of California San Diego, La Jolla
- Stanford University, Palo Alto
- UCLA Medical Center, Santa Monica
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04981119A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
- UC San Diego Medical Center - Encinitas, Encinitas
- Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
- UCI Health - Irvine, Irvine
- and 14 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06989437A Study of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01D/LIGHTBEAM-U01)
- Children's Hospital Los Angeles ( Site 4006), Los Angeles
RecruitingPhase 1/2
1 Month – 17 Years · All sexes · Updated Sep 25, 2026 · NCT07630974A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms
- City of Hope, Duarte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06150157A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer
- CBCC Global Research - Comprehensive Blood & Cancer Center, Bakersfield
- TOI Clinical Research, Cerritos
- University of California, San Diego Moores Cancer Center, La Jolla
- and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06901531Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia
- Quetzal Site 1, Duarte
- Quetzal Site 7, Los Angeles
- Quetzal Site 5, Stanford
RecruitingPhase 3
Ages 18 to 71 · All sexes · Updated Sep 23, 2026 · NCT07504458Intratumoral N17350 in Advanced Solid Tumors
- The Angeles Clinic and Research Institute, Los Angeles
- UCLA - Jonsson Comprehensive Cancer Center, Los Angeles
- Scripps Clinic Torrey Pines - La Jolla, San Diego
- and 1 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07339176A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer
- City of Hope National Medical Center /ID# 281322, Duarte
- City of Hope - Orange County Lennar Foundation Cancer Center /ID# 281396, Irvine
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07365241A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
- City of Hope /ID# 243157, Duarte
- City Of Hope - Seacliff /ID# 263143, Huntington Beach
- City of Hope - Orange County Lennar Foundation Cancer Center /ID# 263144, Irvine
- and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT04928846Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
- UC IRVINE Health, Orange
- UC Davis Comprehensive Cancer Center, Sacramento
- Stanford Cancer Institute, Stanford
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
- Sutter Auburn, Auburn
- Sutter Alta Bates, Berkeley
- The Angeles Clinic and Research Institute, A Cedars-Sinai Affiliate, Los Angeles
- and 19 more
RecruitingPhase 2
Ages 12 and older · All sexes · Updated Sep 22, 2026 · NCT02693535Prospective Study to Assess a Diagnostic Aid for Cancer
- Southern California Research Center, Coronado
- Palomar Health, Poway
- South Coast Gynecologic Oncology, San Diego
RecruitingObservational study
Ages 45 and older · All sexes · Updated Sep 21, 2026 · NCT07046260Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
- City Of Hope, Duarte
- University Of California San Diego Moores Cancer Center, La Jolla
- University of California, San Francisco- California, San Francisco
- and 2 more
RecruitingPhase 2/3
All ages · All sexes · Updated Sep 18, 2026 · NCT03435796A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)
- Childrens Hospital Los Angeles ( Site 3006), Los Angeles
RecruitingPhase 1/2
1 Month – 17 Years · All sexes · Updated Sep 17, 2026 · NCT06941272Statins to Prevent Cancer Associated Blood Clots
- City of Hope, Irvine
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07303816RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
- Kadima Neuropsychiatry Institute, San Diego
- Providence Medical Foundation, Santa Rosa
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07002034Fatigue and Molecular Mechanisms in Cancer Patients Receiving CCRT
- University of California, San Francisco, San Francisco
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06633224(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis
- City of Hope Comprehensive Cancer Center, Duarte
- UCLA Medical Center, Los Angeles
- Stanford Cancer Institute, Stanford
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04996875A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)
- University of Southern California /ID# 272414, Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06953960Exercise and Nutritional Prehabilitation for Head and Neck Cancer Patients
- UC Davis Health, Sacramento
- UC Davis Medical Center, Sacramento
Recruiting
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06722508A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies
- Research Site, Santa Monica
- Research Site, Santa Rosa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT05123482A Study to Investigate Safety and Effectiveness of Tacabrutideg (BGB-16673) in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies
- University of Southern California Norris Comprehensive, Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06634589Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer
- UCI Health Chao Family Comprehensive Cancer Center, Orange
- Investigational Site Number: 403, Palo Alto
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05997615A Phase 1/1b Study of IAM1363 in HER2 Cancers
- UCSD Moores Cancer Center, La Jolla
- USC Norris Comprehensive Cancer Center, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871Post-Marketing Study for Early-Stage Low-Risk Breast Cancer Treatment Using ProSense® Cryoablation (ChoICE Trial)
- Glendale Adventist Medical Center d/b/a Adventist Health Glendale, Glendale
Recruiting
Ages 70 and older · All sexes · Updated Sep 9, 2026 · NCT07629206From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.