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Cancer (all types) clinical trials in Irvine, CA
17 studies for Cancer (all types) are looking for participants at sites in and around Irvine (within about 30 miles). Open a study to see who can join and how to contact the study team.
A Study to Evaluate Adverse Events, Change in Disease Activity, Tolerability, and How Intravenous ABBV-438 Moves Through the Body in Adult Participants With Multiple Myeloma (MM)
RecruitingPhase 1
- City of Hope - Orange County Lennar Foundation Cancer Center /ID# 279067, Irvine
Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma
RecruitingPhase 3
- UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
- Kaiser Permanente-Irvine, Irvine
A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
RecruitingPhase 2/3
- Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
- UCI Health - Irvine, Irvine
A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan, Monotherapy or in Combination With Osimertinib, Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer
RecruitingPhase 2/3
- City of Hope - Orange County Lennar Foundation Cancer Center /ID# 277928, Irvine
A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer
RecruitingPhase 3
- City of Hope - Orange County Lennar Foundation Cancer Center /ID# 281396, Irvine
A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
RecruitingPhase 3
- City of Hope - Orange County Lennar Foundation Cancer Center /ID# 263144, Irvine
Statins to Prevent Cancer Associated Blood Clots
RecruitingPhase 4
- City of Hope, Irvine
A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer
RecruitingPhase 2
- City of Hope Orange County Lennar Foundation Cancer Center, Irvine
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
RecruitingPhase 3
- Hoag Hospital Center, Irvine
- Hoag Hospital Irvine, Irvine
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
RecruitingPhase 3
- Kaiser Permanente-Irvine, Irvine
A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving T Cell Engaging Bi/Tri-specific Antibodies Intravenously (IV)/Subcutaneously (SC) Alone or in Combinations
RecruitingPhase 1/2
- City of Hope - Orange County Lennar Foundation Cancer Center /ID# 277911, Irvine
Biofield Therapy for the Support of Immunotherapy-related Symptoms Among Adult Cancer Patients - A Pilot Study
Recruiting
- UCI Health Susan Samueli Integrative Health Institute, Irvine
Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC
RecruitingPhase 1/2
- City of Hope - Lennar, Irvine
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
RecruitingObservational study
- Massive Bio SYNERGY-AI site, Irvine
Phase 1 Study Evaluating BA3182 in Patients With Advanced Adenocarcinoma.
RecruitingPhase 1
- UC Irvine, Irvine
A Biobehavioral Intervention for Latino/Hispanic Young Adults with Cancer
Recruiting
- University of California, Irvine, Irvine
Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
Recruiting
- UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
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Cancer (all types) trials in other cities
- Houston, TX122 studies
- New York City, NY110 studies
- Boston, MA86 studies
- Los Angeles, CA73 studies
- Nashville, TN65 studies
- Washington, DC60 studies
- Philadelphia, PA60 studies
- Durham, NC59 studies
- Chicago, IL52 studies
- Seattle, WA50 studies
- Atlanta, GA50 studies
- Arlington, VA48 studies
Other studies in Irvine
- Non-Small Cell Lung Cancer25 studies
- Breast Cancer23 studies
- Metastatic Cancer16 studies
- Lung Cancer15 studies
- Prostate Cancer14 studies
- Multiple Myeloma13 studies
- Ovarian Cancer12 studies
- Alzheimer's Disease11 studies
- Head and Neck Squamous Cell Carcinoma11 studies
- Bladder Cancer11 studies
- Pancreatic Cancer10 studies
- Endometrial Cancer10 studies
From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.