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Colon Cancer clinical trials in Florida

29 studies for Colon Cancer are looking for participants at sites in Florida.

Cities in Florida

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

  • Holy Cross Hospital, Fort Lauderdale
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07283939

Family Communications After Genetic Testing

  • Holy Cross Hospital, Fort Lauderdale
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07143487

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

  • Florida Cancer Specialists - South ( Site 7002), Fort Myers
  • Mayo Clinic in Florida ( Site 0092), Jacksonville
  • Orlando Health Cancer Institute ( Site 0065), Orlando
  • and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06997497

A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors

  • ALX Center 7, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07085091

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

  • Florida Cancer Specialists, Bonita Springs
  • Florida Cancer Specialists, Bradenton
  • Comprehensive Hematology Oncology, Brandon
  • and 19 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

  • Florida Cancer Specialists, Sarasota
  • Moffitt Cancer Center and Research Institute, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

  • Florida Cancer Specialists & Research Institute - Sarasota, Sarasota
  • Moffitt Cancer Center, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

  • Florida Oncology & Hematology, Fort Myers
  • University of Florida Health, Gainesville
  • Sylvester Comprehensive Cancer Center, Miami
  • and 4 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07284849

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

  • Memorial Healthcare System, Hollywood
  • The Oncology Institute of Hope & Innovation, Lakeland
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

  • Mount Sinai Comprehensive Cancer Center at Aventura, Aventura
  • Bay Pines VA Healthcare System, Bay Pines
  • Malcom Randall Veterans Administration Medical Center, Gainesville
  • and 8 more
Recruiting
Ages 45 to 70 · All sexes · Updated Sep 2, 2026 · NCT05080673

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

  • AdventHealth Altamonte, Altamonte Springs
  • AdventHealth Celebration, Celebration
  • Morton Plant Hospital, Clearwater
  • and 21 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT05174169

Shield Post-Approval Study Protocol

  • Gastroenterology Consultants of Boca Raton, LLC, Boca Raton
  • Manuel Espinel MD PA, Delray Beach
  • Innova Pharma Research, LLC, Doral
  • and 5 more
RecruitingObservational studyHealthy volunteers welcome
Ages 45 to 81 · All sexes · Updated Aug 7, 2026 · NCT06880055

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

  • Xencor Investigative Site, Jacksonville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT05433142

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

  • Florida Cancer Specialists, Sarasota
  • Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07458347

Integrated Cancer Repository for Cancer Research

  • Florida Hospital Memorial Medical Center, Daytona Beach
  • Florida Hospital DeLand, DeLand
  • Florida Hospital FISH, Orange City
  • and 2 more
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

Utero-ovarian Transposition in Patients With Pelvic Malignancies Undergoing Whole Pelvic Radiotherapy

  • Tampa General Hospital, Tampa
Recruiting
18 Months – 40 Months · Women · Updated Jun 24, 2026 · NCT07419490

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

  • Mayo Clinic, Jacksonville
  • Moffitt Cancer Center, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

  • Research Site, Orlando
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06835569

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

  • Florida Cancer Specialists, Sarasota
  • Lee Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

  • Memorial Healthcare System, Hollywood
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated May 27, 2026 · NCT03093116

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

  • Moffitt Cancer Center, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

A Multilevel Approach to Connecting Underrepresented Populations to Clinical Trials

  • University of Florida, Gainesville
  • Mayo Clinic in Florida, Jacksonville
  • University of Miami, Miami
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated May 8, 2026 · NCT05655494

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

  • Sylvester Comprehensive Cancer Center - University of Miami Health System, Miami
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06239194

Adaptive Randomization of Aerobic Exercise During Chemotherapy in Colon Cancer

  • AdventHealth, Orlando
Recruiting
Ages 18 and older · All sexes · Updated Jan 7, 2026 · NCT05773144

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Jacksonville
  • Massive Bio SYNERGY-AI site, Miami
  • Massive Bio SYNERGY-AI site, Tampa
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

  • Mayo Clinic, Jacksonville
  • Moffitt Cancer Center, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT06682793

Effects of Aerobic Exercise on Skeletal Muscle Remodeling in Colorectal Cancer

  • AdventHealth, Orlando
Recruiting
Ages 18 and older · All sexes · Updated Jul 3, 2025 · NCT05789433

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.