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Colorectal Cancer clinical trials in Indiana

27 studies for Colorectal Cancer are looking for participants at sites in Indiana.

Cities in Indiana

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

  • Baptist Health Floyd, New Albany
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05673148

Colonoscopy vs Stool Testing for Older Adults With Colon Polyps

  • Richard L. Roudebush VA Medical Center, Indianapolis
Recruiting
Ages 65 to 82 · All sexes · Updated Oct 2, 2026 · NCT05612347

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • Reid Health, Richmond
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Family Communications After Genetic Testing

  • Reid Health, Richmond
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07143487

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

  • Exelixis Clinical Site #4, Indianapolis
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

  • Indiana University Simon Comprehensive Cancer Center, Indianapolis
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06625775

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer

  • Indiana University, Simon Comprehensive Cancer Center, Indianapolis
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07659795

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

  • Franciscan Health, Indianapolis
  • Franciscan Health Mooresville, Mooresville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers

  • Community Health Network, Indianapolis
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06663319

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

  • IU Health North Hospital, Carmel
  • Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT05863195

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

  • Community Health Network, Indianapolis
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

  • Indiana University (IU) School of Medicine, Indianapolis
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213791

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

  • Community Health Network, Inc., Indianapolis
  • Hematology Oncology of Indiana, Indianapolis
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07284849

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

  • Clinical Study Site, Fort Wayne
  • Clinical Study Site, Indianapolis
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07228832

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

  • Riley Hospital for Children, Indianapolis
RecruitingPhase 1/2
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

  • Community Health Network, Indianapolis
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06586515

Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy

  • Parkview Cancer Institute, Fort Wayne
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT05014399

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

  • Community Health Network, Indianapolis
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04657068

A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

  • Indiana University, Indianapolis
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT06562543

The Food Environment, Microbial Cysteine Metabolism, and Cancer Disparities

  • University Hospital Clinical Research Center, Indianapolis
  • Purdue Clinical Research Center, West Lafayette
Recruiting
Ages 45 to 75 · All sexes · Updated May 14, 2026 · NCT07086833

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

  • Northwest Cancer Centers, Dyer
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06244771

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

  • Woodland Cancer Care Center, Michigan City
  • Reid Health, Richmond
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

  • Baptist Floyd, New Albany
RecruitingObservational studyHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.