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Head and Neck Squamous Cell Carcinoma clinical trials in Tampa, FL

15 studies for Head and Neck Squamous Cell Carcinoma are looking for participants at sites in and around Tampa (within about 30 miles). Open a study to see who can join and how to contact the study team.

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FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

RecruitingPhase 2/3
  • Site #0105, Tampa
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06788990

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #8, Tampa
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors

RecruitingPhase 1
  • ALX Center 7, Tampa
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07085091

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

RecruitingPhase 3
  • Moffitt Cancer Center, Tampa
Ages 60 and older · All sexes · Updated Sep 25, 2026 · NCT04892173

A Study of JNJ-90301900 in Combination With Chemoradiation Therapy in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma

RecruitingPhase 1
  • Moffit Cancer center, Tampa
Ages 18 to 74 · All sexes · Updated Sep 25, 2026 · NCT07219212

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

RecruitingPhase 2
  • Moffitt Cancer Center-International Plaza, Tampa
  • Moffitt Cancer Center - McKinley Campus, Tampa
  • Moffitt Cancer Center, Tampa
Ages 18 to 79 · All sexes · Updated Sep 22, 2026 · NCT04671667

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

RecruitingPhase 2
  • Moffitt Cancer Center-International Plaza, Tampa
  • Moffitt Cancer Center - McKinley Campus, Tampa
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT02734537

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

RecruitingPhase 2
  • Moffitt Cancer Center-International Plaza, Tampa
  • Moffitt Cancer Center - McKinley Campus, Tampa
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06532279

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT05768139

A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma

RecruitingPhase 3
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Apr 9, 2026 · NCT06064877

A Phase II Study of ACR-368 and Low Dose Gemcitabine in R/M HNSCC

RecruitingPhase 2
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Oct 20, 2025 · NCT06597565

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

RecruitingPhase 1
  • H. Lee Moffitt Cancer Center and Research Institute, Inc, Tampa
Ages 18 and older · All sexes · Updated Aug 15, 2025 · NCT04429542

Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067

RecruitingPhase 1/2
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Nov 15, 2024 · NCT04787042

Head and Neck Squamous Cell Carcinoma trials in other cities

Other studies in Tampa

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.