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Colorectal Cancer clinical trials in Tampa, FL

34 studies for Colorectal Cancer are looking for participants at sites in and around Tampa (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers

RecruitingPhase 1
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07544589

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer

RecruitingPhase 2
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07659795

Colonoscopy vs Stool Testing for Older Adults With Colon Polyps

Recruiting
  • James A. Haley Veterans Hospital, Tampa
Ages 65 to 82 · All sexes · Updated Oct 2, 2026 · NCT05612347

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #8, Tampa
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

RecruitingPhase 1
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06625775

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

RecruitingPhase 1/2
  • H. Lee Moffitt Cancer Center and Research Institute, Tampa
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06324357

A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors

RecruitingPhase 1
  • ALX Center 7, Tampa
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07085091

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

RecruitingObservational study
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04981119

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

RecruitingPhase 1
  • Moffitt, Tampa
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07114601

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

RecruitingPhase 1
  • Moffitt, Tampa
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213791

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

RecruitingPhase 1/2
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06445062

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • Moffitt Cancer Center and Research Institute, Tampa
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

RecruitingPhase 1/2
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960

Multilevel Action Toward Colorectal Cancer and Hepatitis C Education and Screening

RecruitingHealthy volunteers welcome
  • Moffitt Cancer Center, Tampa
Ages 45 to 75 · All sexes · Updated Sep 16, 2026 · NCT06745895

Safety and Efficacy of PIPAC Using Single Agent Mitomycin in Solid Tumors

RecruitingPhase 1
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07487168

A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

RecruitingPhase 1
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT04929223

A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Moffitt Cancer Center, Tampa
Ages 18 to 99 · All sexes · Updated Sep 1, 2026 · NCT06983743

Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Investigative Site #128, Tampa
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT06974110

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

RecruitingPhase 1
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07458347

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • Lee Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

RecruitingPhase 1
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT06917079

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

RecruitingPhase 1/2
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC

RecruitingPhase 2
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Apr 1, 2026 · NCT06553885

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

RecruitingPhase 1
  • H. Lee Moffitt Cancer Center and Research Institute, Inc, Tampa
Ages 18 and older · All sexes · Updated Aug 15, 2025 · NCT04429542

ColoCare Study - Colorectal Cancer Cohort

RecruitingObservational study
  • Lee H. Moffitt Cancer Center, Tampa
Ages 18 to 89 · All sexes · Updated Jun 13, 2025 · NCT02328677

About Colorectal Cancer

Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.

More about Colorectal Cancer on MedlinePlus

Colorectal Cancer trials in other cities

Other studies in Tampa

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.