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Kidney Cancer (Renal Cell Carcinoma) clinical trials in Nashville, TN

23 studies for Kidney Cancer (Renal Cell Carcinoma) are looking for participants at sites in and around Nashville (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors

RecruitingPhase 1
  • Research Site, Nashville
  • Research Site, Nashville
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT05536141

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Tennessee Oncology, Nashville
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06270706

A Phase 1 Study of the Safety and Tolerability of CTX-10726

RecruitingPhase 1
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07419841

Substudy 03C: A Study of Combination Therapies in Participants With Renal Cell Carcinoma With Recurrent Disease During or After Anti-PD-(L)1 Therapy (MK-3475-03C/KEYMAKER-U03)

RecruitingPhase 1/2
  • Vanderbilt University Medical Center ( Site 5004), Nashville
Ages 18 to 120 · All sexes · Updated Oct 2, 2026 · NCT07049926

A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma

RecruitingPhase 1
  • Sarah Cannon Research Institute (SCRI), Nashville
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06234605

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #3, Nashville
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

RecruitingPhase 2
  • Vanderbilt University/Ingram Cancer Center, Nashville
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

DESTINY-PANTUMOUR04

RecruitingObservational study
  • Research Site, Nashville
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

RecruitingObservational study
  • Vanderbilt University Medical Center, Nashville
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04981119

Casdatifan for the Treatment of Refractory Metastatic Clear Cell Renal Cell Carcinoma

RecruitingPhase 1
  • Vanderbilt University Medical Center, Nashville
Ages 18 to 100 · All sexes · Updated Sep 25, 2026 · NCT07748988

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

RecruitingPhase 1/2
  • Vanderbilt University Medical Center, Nashville
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06047379

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

RecruitingPhase 1/2
  • Sarah Cannon Research Institute, Nashville
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05267626

Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

RecruitingPhase 1/2
  • Sarah Cannon Research Institute, Nashville
  • SCRI Oncology Partners, Nashville
  • Tennessee Oncology, PLLC- Elliston Place Plaza, Nashville
  • and 11 more
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07227415

A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies

RecruitingPhase 1
  • Scri Oncology Partners, Nashville
  • Vanderbilt Medical Center, Nashville
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07195916

A Randomized Trial of Fianlimab and Cemiplimab +/- Ipilimumab or Ipilimumab Plus Nivolumab in First-line Advanced Renal Cell Carcinoma (RCC)

RecruitingPhase 2
  • Vanderbilt-Ingram Cancer Center, Nashville
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07188896

Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

RecruitingPhase 3
  • Vanderbilt University/Ingram Cancer Center, Nashville
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06661720

Genetic Testing to Select Therapy for the Treatment of Advanced or Metastatic Kidney Cancer, OPTIC RCC Study

RecruitingPhase 2
  • Vanderbilt University/Ingram Cancer Center, Nashville
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT05361720

Study of DCC-2812 in Participants With Advanced Genitourinary Cancers

RecruitingPhase 1
  • Vanderbilt- Ingram Cancer Center, Nashville
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06966024

A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Vanderbilt University Medical Center, Nashville
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT04895709

A First-in-Human Study of BMS-986506 in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC)

RecruitingPhase 1
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT07195682

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

RecruitingPhase 1
  • Xencor Investigative Site, Nashville
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT05433142

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

RecruitingPhase 1
  • SCRI - Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT06026410

Pilot Study of Bone Mineral Density Changes During Anti-PD-1 Immunotherapy

Recruiting
  • Vanderbilt-Ingram Cancer Center, Nashville
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT07555210

Kidney Cancer (Renal Cell Carcinoma) trials in other cities

Other studies in Nashville

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.