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Small Cell Lung Cancer clinical trials in Houston, TX

26 studies for Small Cell Lung Cancer are looking for participants at sites in and around Houston (within about 30 miles). Open a study to see who can join and how to contact the study team.

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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07189871

Symbiotic-Lung-04: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Extensive-Stage Small Cell Lung Cancer

RecruitingPhase 2/3
  • Texas Oncology - Gulf Coast, Houston
  • Texas Oncology - Gulf Coast, Houston
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07226999

A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer

RecruitingPhase 3
  • The University of Texas MD Anderson Cancer Center /ID# 280070, Houston
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07365241

A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors

RecruitingPhase 1/2
  • Next Oncology - Houston, Houston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07488676

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

RecruitingPhase 1
  • Oncology Consultants, P.A., Houston
  • University of Texas M.D. Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05983432

A Study of YL201 in Combination With Other Anti-Cancer Therapies in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Site 1005, Houston
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07407933

A Study to Evaluate DJI136, a DLL3-targeted CAR-T Therapy

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT07564401

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

RecruitingPhase 1/2
  • Avenzo Therapeutics Recruiting Site, Houston
Ages 18 to 75 · All sexes · Updated Sep 4, 2026 · NCT07038343

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

RecruitingPhase 3
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT06712355

Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and in Patients With Other Advanced Solid Tumors

RecruitingPhase 1/2
  • MD Anderson Cancer Center Uni of Te, Houston
Ages 18 to 100 · All sexes · Updated Aug 27, 2026 · NCT06726148

A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT06892548

A First-in-human (FIH), Phase 1 Study of ML261, an Autologous Potency Enhanced Anti-DLL3 CAR T Cell Therapy, in Participants With R/R SCLC or Select NECs (SPECTRAL-1)

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07488923

A Study of MGC026 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • The University of Texas MD Anderson Cancer Center, Houston
  • University of Texas Health Science Center at Houston, Houston
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT06242470

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • The University of Texas, MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626

A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer

RecruitingPhase 3
  • Houston Methodist Cancer Center, Houston
  • University of Texas Md Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT06203210

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

RecruitingPhase 1
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT06131840

A Study of IDE849 in Patients With DLL3 Expressing Tumors Including Small Cell Lung Cancer

RecruitingPhase 1/2
  • The University of Texas MD Anderson Cancer Center, Houston
  • Oncology Consultants, PA- Houston, Houston
Ages 18 and older · All sexes · Updated Jul 9, 2026 · NCT07174583

Subcutaneous Tarlatamab in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-308)

RecruitingPhase 1
  • University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jun 26, 2026 · NCT06598306

A Study of LY4175408 in Participants With Advanced Cancer

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT07046923

Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

RecruitingPhase 2
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Mar 30, 2026 · NCT06769126

Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLC

RecruitingPhase 1/2
  • Michael E. DeBakey VA Medical Center, Houston, TX, Houston
Ages 18 and older · All sexes · Updated Mar 11, 2026 · NCT06681220

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

RecruitingPhase 1/2
  • The University of Texas MD Anderson Cancer Center (site 127), Houston
Ages 18 to 80 · All sexes · Updated Dec 11, 2025 · NCT03556228

A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit

RecruitingPhase 1
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 23, 2025 · NCT06805825

A Phase 1 Dose Escalation Study of ZG006 in Patients With Small Cell Lung Cancer

RecruitingPhase 1
  • Zelgen Site 106, Houston
Ages 18 to 75 · All sexes · Updated Aug 6, 2025 · NCT06592638

Small Cell Lung Cancer trials in other cities

Other studies in Houston

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.