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Acute Myeloid Leukemia clinical trials in Winston-Salem, NC

18 studies for Acute Myeloid Leukemia are looking for participants at sites in and around Winston-Salem (within about 30 miles). Open a study to see who can join and how to contact the study team.

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MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

RecruitingPhase 2
  • Novant Health Forsyth Medical Center, Winston-Salem
  • Wake Forest University Health Sciences, Winston-Salem
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT05564390

Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

RecruitingPhase 1
  • Wake Forest University Health Sciences, Winston-Salem
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06484062

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

RecruitingPhase 2
  • Novant Health Forsyth Medical Center, Winston-Salem
  • Wake Forest University Health Sciences, Winston-Salem
Ages 18 to 59 · All sexes · Updated Sep 28, 2026 · NCT05554393

A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

RecruitingPhase 3
  • Novant Health Winston Salem, Winston-Salem
  • Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06852222

Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)

RecruitingPhase 2
  • Wake Forest University Health Sciences, Winston-Salem
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06672146

Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

RecruitingPhase 2
  • Wake Forest University Health Sciences, Winston-Salem
Ages 18 to 59 · All sexes · Updated Sep 22, 2026 · NCT05554406

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

RecruitingPhase 2
  • Wake Forest University Health Sciences, Winston-Salem
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06317649

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

RecruitingPhase 3
  • Wake Forest University Health Sciences, Winston-Salem
6 Months – 21 Years · All sexes · Updated Sep 17, 2026 · NCT04293562

Olutasidenib in Relapsed IDH1 Mutated AML Patients Who Have Previously Received Venetoclax

RecruitingPhase 2
  • Atrium Health Wake Forest Baptist Medical Center, Winston-Salem
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07471841

Toxicity Genetic Determinants and Response to Azacitidine and Venetoclax in AML

RecruitingObservational study
  • Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT06580106

ONC-LEUK-2406: The Impact of Systematic Financial Navigation in Acute Myeloid Leukemia

Recruiting
  • Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem
Ages 18 to 64 · All sexes · Updated Jul 23, 2026 · NCT06945042

Tagraxofusp and Azacitidine With Venetoclax in Newly Diagnosed Secondary AML After Hypomethylating Agents

RecruitingPhase 2
  • Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT05442216

A Decisional Intervention for Older Adults With Acute Myeloid Leukemia and Their Caregivers

Recruiting
  • Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Section of Hematology/Oncology, Winston-Salem
Ages 60 and older · All sexes · Updated Jul 6, 2026 · NCT06697600

The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen

RecruitingObservational study
  • Wake Forest Baptist Health, Winston-Salem
Ages 18 to 120 · All sexes · Updated Apr 13, 2026 · NCT01890486

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

RecruitingPhase 1/2
  • Atrium Wake Forest Baptist Medical Center, Winston-Salem
Ages 12 and older · All sexes · Updated Mar 24, 2026 · NCT04988555

Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS

RecruitingPhase 1/2
  • Novant Health Cancer Institute, Winston-Salem
Ages 18 and older · All sexes · Updated Dec 10, 2025 · NCT06680752

About Acute Myeloid Leukemia

Acute Myeloid Leukemia (AML) is a cancer of the white blood cells. AML usually gets worse quickly if it is not treated. Read more.

More about Acute Myeloid Leukemia on MedlinePlus

Acute Myeloid Leukemia trials in other cities

Other studies in Winston-Salem

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.