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Acute Myeloid Leukemia clinical trials in Columbus, OH

34 studies for Acute Myeloid Leukemia are looking for participants at sites in and around Columbus (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

RecruitingPhase 2
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06317649

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

RecruitingPhase 3
  • Ohio State University, Columbus
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07007312

Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

RecruitingPhase 2
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 to 59 · All sexes · Updated Nov 9, 2026 · NCT05554406

Ziftomenib for the Treatment of Patients With NPM1 Mutated or KMT2A Rearranged Acute Myeloid Leukemia Not Eligible for Standard Therapy

RecruitingPhase 2
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT06930352

HPC Offered for PRESERVE Expansion

RecruitingObservational study
  • The Ohio State University Medical Center, Columbus
Ages 12 to 80 · All sexes · Updated Nov 6, 2026 · NCT07145411

Bleximenib in Combination With Standard Induction and Consolidation Therapy Followed by Maintenance for Treatment of Patients With Acute Myeloid Leukemia (AML)

RecruitingPhase 3
  • US-Colombus OH-OSU, Columbus
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT07223814

Comparing Different Treatment Lengths for Venetoclax in Older People With Newly Diagnosed Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

RecruitingPhase 2
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 60 and older · All sexes · Updated Nov 6, 2026 · NCT07437950

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Ohio State University Comprehensive Cancer Center, Columbus
  • Mount Carmel East Hospital, Columbus
  • The Mark H Zangmeister Center, Columbus
  • and 8 more
Ages 40 to 75 · All sexes · Updated Nov 4, 2026 · NCT05334069

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

RecruitingPhase 2
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT05564390

A Study to Assess the Safety, Tolerability, and Antileukemic Activity of Debio 1562M in Participants With Acute Myeloid Leukemia (AML)

RecruitingPhase 1/2
  • The Ohio Sate University, Columbus
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT06969430

Eganelisib as Monotherapy and in Combination With Cytarabine in Relapsed/Refractory AML/HR-MDS and in Combination With Azacitidine in Previously Untreated HR-MDS

RecruitingPhase 1
  • Ohio State University, Columbus
Ages 18 and older · All sexes · Updated Oct 20, 2026 · NCT06533761

Phase 1 Study of AUTX-703 in Relapsed/Refractory AML and MDS

RecruitingPhase 1
  • Ohio State University, The James Comprehensive Cancer, Columbus
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT06846606

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

RecruitingPhase 1/2
  • Ohio State University, Columbus
30 Days · All sexes · Updated Oct 9, 2026 · NCT04065399

A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies

RecruitingObservational study
  • OhioHealth Research Institute, Columbus
Ages 0 and older · All sexes · Updated Oct 9, 2026 · NCT07154823

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

RecruitingPhase 2/3
  • Ohio State University Comprehensive Cancer Center (OSUCCC) - The James Cancer Hospital and Solove Research Institute, Columbus
Ages 18 and older · All sexes · Updated Oct 6, 2026 · NCT04256317

Ziftomenib Maintenance Post Allo-HCT

RecruitingPhase 1
  • Ohio State University Wexner Medical Center- James Cancer Hospital, Columbus
Ages 18 and older · All sexes · Updated Oct 6, 2026 · NCT06440135

Ivosidenib as Post-HSCT Maintenance for AML

RecruitingPhase 2
  • Ohio State University Wexner Medical Center- James Cancer Hospital, Columbus
Ages 18 to 75 · All sexes · Updated Oct 5, 2026 · NCT06707493

Ruxolitinib in Combination With Venetoclax With and Without Azacitidine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

RecruitingPhase 1
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT03874052

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

RecruitingPhase 3
  • Nationwide Children's Hospital, Columbus
6 Months – 21 Years · All sexes · Updated Sep 17, 2026 · NCT04293562

Vyxeos for Re-induction Treatment of Acute Myeloid Leukemia Patients With Persistent Disease After Induction

RecruitingPhase 1/2
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 to 75 · All sexes · Updated Sep 9, 2026 · NCT04049539

Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML

RecruitingPhase 3
  • US-Colombus OH-OSU, Columbus
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06652438

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

RecruitingObservational study
  • Nationwide Children's Hospital, Columbus
  • The Arthur G. James Cancer Hospital/The Ohio State University Medical Center, Columbus
All ages · All sexes · Updated Jul 6, 2026 · NCT01351545

IDH Targeted/Non- Targeted vs Non-targeted/IDH-targeted Approaches in the Treatment of Newly Diagnosed IDH Mutated AML Patients Not Candidates for Intensive Induction Therapy (I- DATA Study)

RecruitingPhase 2
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT05401097

SNDX-5613 and Gilteritinib for the Treatment of Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia and Concurrent MLL-Rearrangement or NPM1 Mutation

RecruitingPhase 1
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated May 14, 2026 · NCT06222580

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

RecruitingPhase 1
  • The Ohio State University, Columbus
Ages 13 and older · All sexes · Updated May 5, 2026 · NCT04771572

Expanded/Activated Gamma Delta T-cell Infusion Following Hematopoietic Stem Cell Transplantation and Post-transplant Cyclophosphamide

RecruitingPhase 1
  • Ohio State University Medical Center, Columbus
Ages 18 to 65 · All sexes · Updated Mar 25, 2026 · NCT03533816

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

RecruitingPhase 1/2
  • The Ohio State University Comprehensive Cancer Center, Columbus
Ages 12 and older · All sexes · Updated Mar 24, 2026 · NCT04988555

A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

RecruitingPhase 1
  • The James Cancer Hospital and Solove Research Institute, Columbus
Ages 18 and older · All sexes · Updated Mar 13, 2026 · NCT05735184

A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome

RecruitingPhase 1
  • The Ohio State University Wexner Medical Center - James Cancer Hosp, Columbus
Ages 18 and older · All sexes · Updated Sep 24, 2025 · NCT06501196

Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia

RecruitingPhase 1/2
  • The Ohio State University Wexner Medical Center, Columbus
Ages 18 and older · All sexes · Updated Aug 26, 2025 · NCT03850574

Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

RecruitingHealthy volunteers welcome
  • Ohio State University, Columbus
Ages 18 to 120 · All sexes · Updated Jul 25, 2025 · NCT05237258

Safety and Efficacy of Expanded, Universal Donor Natural Killer Cells for Relapsed/Refractory AML

RecruitingPhase 1/2
  • Nationwide Children's Hospital, Columbus
Ages 1 to 24 · All sexes · Updated Nov 4, 2024 · NCT05503134

About Acute Myeloid Leukemia

Acute Myeloid Leukemia (AML) is a cancer of the white blood cells. AML usually gets worse quickly if it is not treated. Read more.

More about Acute Myeloid Leukemia on MedlinePlus

Acute Myeloid Leukemia trials in other cities

Other studies in Columbus

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.