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Cardiovascular Disease clinical trials in Charlotte, NC

9 studies for Cardiovascular Disease are looking for participants at sites in and around Charlotte (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

RecruitingPhase 4
  • Novant Health Clinical Research/Heart & Vascular Institute, Charlotte
  • Mecklenburg Heart Specialists, Charlotte
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06909565

CARE-CP (Testing a Cardiovascular Ambulatory Rapid Evaluation for Patients With Chest Pain)

Recruiting
  • Carolinas Medical Center, Charlotte
Ages 21 and older · All sexes · Updated Sep 30, 2026 · NCT05897632

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

RecruitingPhase 3
  • Piedmont Research Partners, LLC, Fort Mill · 16 mi away
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07064473

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

RecruitingPhase 3
  • Clinical Trial Site, Monroe · 24 mi away
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07181109

An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

RecruitingPhase 3
  • Novant Health Heart Vas Inst, Charlotte
Ages 18 to 100 · All sexes · Updated Sep 4, 2026 · NCT07517263

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • Atrium Health, Charlotte
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

RecruitingPhase 3
  • Research Site, Charlotte
  • Research Site, Charlotte
  • Research Site, Fort Mill · 16 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

RecruitingPhase 3
  • Monroe Biomedical Research, Monroe · 24 mi away
Ages 50 to 105 · All sexes · Updated Aug 21, 2026 · NCT07136012

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Recruiting
  • Carolinas Medical Center, Charlotte
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

Cardiovascular Disease trials in other cities

Other studies in Charlotte

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.