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Cardiovascular Disease clinical trials in Pittsburgh, PA

20 studies for Cardiovascular Disease are looking for participants at sites in and around Pittsburgh (within about 30 miles). Open a study to see who can join and how to contact the study team.

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

RecruitingPhase 3
  • Preferred Primary Care Physicians-Pittsburgh-63932, Pittsburgh
  • Preferred Primary Care Physicians, Inc, Pittsburgh
  • Heritage Valley Medical Group, Beaver · 24 mi away
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07064473

Transition to Cardiac Rehabilitation (T2CR) to Address Barriers of Multimorbidity and Frailty

Recruiting
  • VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06244199

Treatment With Aspirin After Preeclampsia: TAP Trial

RecruitingPhase 4
  • University of Pittsburgh Magee-Womens Hospital, Pittsburgh
Ages 18 to 55 · Women · Updated Sep 22, 2026 · NCT06281665

Product Surveillance Registry

RecruitingObservational study
  • Pittsburgh, Pittsburgh
All ages · All sexes · Updated Sep 18, 2026 · NCT01524276

Zenith® Fenestrated+ Clinical Study

Recruiting
  • University of Pittsburgh Medical Center, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT04875429

Cerebrovascular Health and Resilience in Midlife

RecruitingHealthy volunteers welcome
  • University of Pittsburgh, Pittsburgh
Ages 40 to 59 · All sexes · Updated Sep 16, 2026 · NCT06029348

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Recruiting
  • UPMC Presbyterian, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642

Feasibility of The Health Integrated Nutrition and Kidney Wellness Program

Recruiting
  • UPMC Kidney Clinic - Wexford, Pittsburgh
  • UPMC Kidney Clinic - Monroeville, Pittsburgh
  • UPMC Kidney Clinic - Oakland, Pittsburgh
  • and 2 more
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07518719

An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

RecruitingPhase 3
  • Allegheny General Hospital, Pittsburgh
Ages 18 to 100 · All sexes · Updated Sep 4, 2026 · NCT07517263

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • University of Pittsburgh Medical Center, Pittsburgh
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma

RecruitingObservational study
  • Children's Hospital of Pittsburgh of UPMC, Pittsburgh
Ages 7 and older · All sexes · Updated Aug 25, 2026 · NCT05705531

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

RecruitingPhase 3
  • Research Site, Pittsburgh
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

RecruitingPhase 3
  • Preferred Primary Care Physicians, Inc, Pittsburgh
Ages 50 to 105 · All sexes · Updated Aug 21, 2026 · NCT07136012

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Recruiting
  • UPMC, Pittsburgh
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Recruiting
  • Allegheny General Hospital, Pittsburgh
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

Brain Connections for Arm Movement After Stroke

RecruitingHealthy volunteers welcome
  • VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA, Pittsburgh
Ages 45 to 90 · All sexes · Updated Jun 2, 2026 · NCT04286516

Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke

Recruiting
  • University of Pittsburgh, Pittsburgh
Ages 18 to 75 · All sexes · Updated May 8, 2026 · NCT06303869

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Recruiting
  • Allegheny Health Network, Pittsburgh
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels

Recruiting
  • University of Pittsburgh Medical center (UPMC), Pittsburgh
Ages 18 to 80 · All sexes · Updated Sep 11, 2025 · NCT06271590

PARTNER 3 Trial - Aortic Valve-in-Valve

Recruiting
  • Allegheny General Hospital, Pittsburgh
All ages · All sexes · Updated May 10, 2024 · NCT03003299

Cardiovascular Disease trials in other cities

Other studies in Pittsburgh

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.