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Cardiovascular Disease clinical trials in Houston, TX

24 studies for Cardiovascular Disease are looking for participants at sites in and around Houston (within about 30 miles). Open a study to see who can join and how to contact the study team.

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

RecruitingPhase 3
  • Victorium Clinical Research, Houston
  • Houston Research Institute, Houston
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07064473

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

RecruitingPhase 2
  • Cardiovascular Specialists of Willowbrook, Houston
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07783802

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

RecruitingPhase 4
  • Vital Heart and Vein, Humble · 17 mi away
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06909565

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

RecruitingPhase 3
  • Clinical Trial Site, Houston
  • Clinical Trial Site, Houston
  • Clinical Trial Site, Houston
  • and 7 more
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07181109

Product Surveillance Registry

RecruitingObservational study
  • Houston, Houston
All ages · All sexes · Updated Sep 18, 2026 · NCT01524276

Zenith® Fenestrated+ Clinical Study

Recruiting
  • Memorial Hermann Texas Medical Center/UT Health, Houston
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT04875429

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Recruiting
  • CHI Saint Luke's Health-Baylor Saint Luke's Medical Center, Houston
  • Houston Methodist Hospital, Houston
  • The University of Texas Health Science Center at Houston, Houston
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

Recruiting
  • Houston Methodist Hospital, Houston
  • Memorial Hermann-Texas Medical Center, Houston
  • Texas Heart Institute at Baylor St. Luke's Medical Center, Houston
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

RecruitingPhase 3
  • Baylor College Of Medicine, Houston
Ages 18 to 100 · All sexes · Updated Sep 4, 2026 · NCT07517263

A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD

RecruitingPhase 2
  • Clinical Research Site, Houston
Ages 18 to 85 · All sexes · Updated Sep 2, 2026 · NCT07333183

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • University of Texas at Houston, Houston
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma

RecruitingObservational study
  • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston
Ages 7 and older · All sexes · Updated Aug 25, 2026 · NCT05705531

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

RecruitingPhase 3
  • Research Site, Houston
  • Research Site, Houston
  • Research Site, Houston
  • and 4 more
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

RecruitingPhase 3
  • East Texas Cardiology PA, Houston
  • Baylor College of Medicine, Houston
  • Cardiovascular Specialists of Willowbrook, Houston
  • and 1 more
Ages 50 to 105 · All sexes · Updated Aug 21, 2026 · NCT07136012

Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD

RecruitingPhase 3
  • Kelsey Seybold Research Foundation, Houston
Ages 18 to 80 · All sexes · Updated Aug 7, 2026 · NCT06813911

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Recruiting
  • Baylor/Texas Heart, Houston
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Recruiting
  • CHI St. Luke's Health Baylor College of Medicine Medical Center, Houston
  • Houston Methodist, Houston
  • UTHealth Memorial Hermann, Houston
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

Pivotal Study for the Cardiac Performance System (CPS)

RecruitingObservational study
  • Baylor College of Medicine, Houston
Ages 18 and older · All sexes · Updated Apr 24, 2026 · NCT06870591

DeBakey Cardiovascular Magnetic Resonance Study

RecruitingObservational studyHealthy volunteers welcome
  • Houston Methodist Hospital, Houston
All ages · All sexes · Updated Apr 20, 2026 · NCT04281823

Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary Computed Tomography Angiography Trial

RecruitingPhase 3
  • Vital Heart and Vein, Humble · 17 mi away
Ages 35 to 80 · All sexes · Updated Apr 16, 2026 · NCT07293260

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Recruiting
  • Houston Healthcare Medical Center, Houston
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Randomized Trial of SGLT2i in Heart Transplant Recipients

RecruitingPhase 4
  • Michael E. DeBakey VA Medical Center, Houston, TX, Houston
Ages 18 and older · All sexes · Updated Jan 22, 2026 · NCT06625073

Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial)

RecruitingPhase 2
  • UT Health Houston, Houston
Ages 40 and older · All sexes · Updated Dec 17, 2025 · NCT05488431

PARTNER 3 Trial - Aortic Valve-in-Valve

Recruiting
  • The University of Texas Health Science Center at Houston, Houston
All ages · All sexes · Updated May 10, 2024 · NCT03003299

Cardiovascular Disease trials in other cities

Other studies in Houston

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.