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Drug Use and Addiction clinical trials in Charleston, SC

8 studies for Drug Use and Addiction are looking for participants at sites in and around Charleston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Endocannabinoids in Reward

RecruitingPhase 2
  • Medical University of South Carolina, Charleston
Ages 21 to 45 · All sexes · Updated Oct 5, 2026 · NCT07815691

Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People

RecruitingHealthy volunteers welcome
  • National Crime Victims Research and Treatment Center, Charleston
Ages 15 to 30 · All sexes · Updated Sep 9, 2026 · NCT05816083

STEPS: Substance Use Trial of E-cigarettes or Pharmacotherapy for Smoking

RecruitingHealthy volunteers welcome
  • MUSC Charleston, Charleston
Ages 21 and older · All sexes · Updated Sep 3, 2026 · NCT06922617

CARS: Cannabis and Alcohol Reduction Study

Recruiting
  • Medical University of South Carolina, Charleston
Ages 13 to 17 · All sexes · Updated Aug 13, 2026 · NCT05486234

COPEWeb Training for Providers

RecruitingHealthy volunteers welcome
  • Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT05812131

Technology-Enhanced Therapy vs. Medication Monitoring for Buprenorphine Retention in Pregnant Persons

Recruiting
  • Medical University of South Carolina, Charleston
Ages 18 to 45 · Women · Updated Apr 8, 2026 · NCT06999811

MPFC Theta Burst Stimulation as a Treatment Tool for Alcohol Use Disorder: Effects on Drinking and Incentive Salience

Recruiting
  • Medical University of South Carolina, Charleston
Ages 21 to 65 · All sexes · Updated Apr 2, 2026 · NCT04998916

Integrated Treatment for Opioid Use Disorder and PTSD

Recruiting
  • Medical University of South Carolina, Charleston
Ages 18 to 70 · All sexes · Updated Nov 28, 2025 · NCT06641115

About Drug Use and Addiction

Drugs include prescription and over-the-counter medicines, alcohol, tobacco, and illegal substances. Repeated drug use can change the brain and lead to addiction.

More about Drug Use and Addiction on MedlinePlus

Drug Use and Addiction trials in other cities

Other studies in Charleston

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.