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Drug Use and Addiction clinical trials in Chicago, IL

7 studies for Drug Use and Addiction are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Massed Prolonged Exposure for PTSD in Substance Use Treatment

Recruiting
  • Hines VA Healthcare System, Chicago
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT06296186

Multi-Site Trial of Tirzepatide for Smoking Cessation

RecruitingPhase 2
  • University of Chicago Pritzker School of Medicine, Chicago
Ages 21 to 65 · All sexes · Updated Jul 17, 2026 · NCT07602699

The Trans-Led Care Study

Recruiting
  • Illinois Institute of Technology, Chicago
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT06880705

Implementation of Tobacco Cessation Programming at Community Behavioral Health Sites

Recruiting
  • The University of Chicago, Chicago
Ages 18 to 26 · All sexes · Updated Jul 7, 2026 · NCT06837220

J-RISE: Relevant Implementation Strategies to Eliminate the Social and Structural Barriers to HIV Services Among Justice-involved Black Men Who Have Sex With Men and Other Key Populations

RecruitingHealthy volunteers welcome
  • University of Chicago, Chicago
Ages 18 and older · All sexes · Updated Apr 21, 2026 · NCT06477588

Family Support Protocol for Adolescent Internalizing Disorders

Recruiting
  • Lurie Children's Hospital, Chicago
Ages 13 to 21 · All sexes · Updated Apr 17, 2026 · NCT06413979

Testing the Effectiveness and Implementation of a Meditation App for Youth in the Legal System

RecruitingHealthy volunteers welcome
  • University of Illinois at Chicago, Chicago
Ages 13 to 20 · All sexes · Updated Mar 10, 2026 · NCT06997120

About Drug Use and Addiction

Drugs include prescription and over-the-counter medicines, alcohol, tobacco, and illegal substances. Repeated drug use can change the brain and lead to addiction.

More about Drug Use and Addiction on MedlinePlus

Drug Use and Addiction trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.