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Lung Cancer clinical trials in Rochester, MN

20 studies for Lung Cancer are looking for participants at sites in and around Rochester (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Cemiplimab and Fianlimab Before Surgery for the Treatment of Stage IB-IIIB Non-Small Cell Lung Cancer

RecruitingPhase 2
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06918132

A Study to Investigate Ubamatamab With and Without Marlotamig (REGN7075) in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

RecruitingPhase 2
  • Mayo Clinic, Rochester
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07154290

Molecular Analysis of Suspected or High-Risk Lung Cancer to Drive Individualized Care

RecruitingObservational study
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06482073

A Tool for Improving the Shared Decision-making Process in Patients With Non-small Cell Lung Cancer

RecruitingHealthy volunteers welcome
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT06122064

Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung

RecruitingPhase 3
  • Mayo Clinic, Rochester
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07499674

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

RecruitingPhase 3
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06500481

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

RecruitingPhase 3
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05624996

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

RecruitingPhase 1
  • Xencor Investigative Site, Rochester
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT05433142

Evaluation of Anti-PD-1 Therapy by Monitoring T Cell Responses in Melanoma, Lung and Other Cancer Types

RecruitingObservational study
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT06075524

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • Mayo Clinic Rochester, Rochester
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

The Sarah Nanotechnology System for Treatment of Advanced Metastatic Solid Tumors Using Hyperthermia.

Recruiting
  • Mayo Clinic, Rochester
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT07224464

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

RecruitingPhase 1/2
  • Mayo Clinic Cancer Center, Rochester
Ages 18 and older · All sexes · Updated May 14, 2026 · NCT06922591

Grid Radiation Therapy for the Treatment of Stage IV Non-Small Cell Lung Cancer

RecruitingPhase 2
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06660407

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

RecruitingPhase 1/2
  • Mayo Clinic Cancer Center, Rochester
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06810544

Insomnia in Patients With Metastatic Lung Cancer

RecruitingObservational study
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Feb 4, 2026 · NCT06472804

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic, Rochester
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

Thoracic Specimen Registry

RecruitingObservational study
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Jan 16, 2026 · NCT04118660

About Lung Cancer

Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.

More about Lung Cancer on MedlinePlus

Lung Cancer trials in other cities

Other studies in Rochester

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.