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Colorectal Cancer clinical trials in Rochester, MN
29 studies for Colorectal Cancer are looking for participants at sites in and around Rochester (within about 30 miles). Open a study to see who can join and how to contact the study team.
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
RecruitingPhase 3
- Mayo Clinic Hospital, Methodist Campus, Research Pharmacy, Rochester
- Mayo Clinic Pharmacy, Rochester
- Mayo Clinic Cancer Center Outpatient Pharmacy, Rochester
- and 3 more
Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
RecruitingObservational study
- Mayo Clinic Rochester, Rochester
Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial
RecruitingPhase 3
- Mayo Clinic in Rochester, Rochester
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
RecruitingPhase 1
- Mayo Clinic - Rochester, Rochester
Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
RecruitingPhase 1/2
- Mayo Clinic, Rochester
An Investigational Drug (TPST-1495) in Patients With Familial Adenomatous Polyposis
RecruitingPhase 2
- Mayo Clinic in Rochester, Rochester
A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)
RecruitingPhase 1
- Mayo Clinic Rochester, Rochester
PRE-ISPY Phase I/II Oncology Platform Program
RecruitingPhase 1/2
- Mayo Clinic Comprehensive Cancer Center, Rochester
A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer
RecruitingPhase 2
- Research Site, Rochester
Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients
RecruitingObservational study
- Mayo Clinic, Rochester
FOG-001 in Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
- Mayo Clinic, Rochester
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
RecruitingPhase 1
- Exelixis Clinical Site #68, Rochester
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
- Mayo Clinic (Minnesota), Rochester
Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers
RecruitingPhase 1
- Mayo Clinic Rochester, Rochester
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
RecruitingPhase 3
- Mayo Clinic Cancer Center Outpatient Pharmacy, Rochester
A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors
RecruitingPhase 1
- Mayo Clinic Cancer Center, Rochester
- Mayo Clinic, Rochester
A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer
RecruitingPhase 2
- May Clinic Rochester, Rochester
A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
RecruitingPhase 2
- Mayo Clinic-Rochester /ID# 273508, Rochester
Lead-212 PSV359 Therapy for Patients With Solid Tumors
RecruitingPhase 1/2
- Mayo Clinic in Rochester, Minnesota, Rochester
A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
RecruitingPhase 1/2
- Mayo Clinic Rochester, Rochester
KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors
RecruitingPhase 1
- Mayo Clinic Comprehensive Cancer Center, Rochester
A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies
RecruitingPhase 1
- Mayo Clinic, Rochester, Rochester
A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
RecruitingPhase 1/2
- Mayo Clinic, Rochester
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
RecruitingObservational study
- Mayo Clinic, Rochester
Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform
RecruitingObservational study
- Mayo Clinic in Rochester, Rochester
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration
RecruitingPhase 1/2
- Mayo Clinic, Rochester
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
RecruitingPhase 1/2
- Mayo Clinic, Rochester
A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)
RecruitingPhase 1/2
- Mayo Clinic in Minnesota, Rochester
About Colorectal Cancer
Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.
More about Colorectal Cancer on MedlinePlus
Colorectal Cancer trials in other cities
- Houston, TX101 studies
- New York City, NY77 studies
- Nashville, TN68 studies
- Boston, MA63 studies
- Los Angeles, CA59 studies
- Arlington, VA52 studies
- St. Louis, MO49 studies
- San Antonio, TX46 studies
- Philadelphia, PA44 studies
- Grand Rapids, MI40 studies
- Baldwin Park, CA38 studies
- Seattle, WA34 studies
Other studies in Rochester
- Breast Cancer42 studies
- Non-Small Cell Lung Cancer38 studies
- Cancer (all types)31 studies
- Metastatic Cancer30 studies
- Ovarian Cancer29 studies
- Multiple Myeloma23 studies
- Pancreatic Cancer23 studies
- Heart Failure22 studies
- Prostate Cancer22 studies
- Lung Cancer20 studies
- Endometrial Cancer19 studies
- Chronic Lymphocytic Leukemia19 studies
From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.