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Breast Cancer clinical trials in Rochester, MN
42 studies for Breast Cancer are looking for participants at sites in and around Rochester (within about 30 miles). Open a study to see who can join and how to contact the study team.
Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy
Recruiting
- Mayo Clinic, Rochester
ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer
RecruitingPhase 2
- Mayo Clinic Cancer Center, Rochester
Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
Recruiting
- Mayo Clinic, Rochester
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
RecruitingPhase 3
- Mayo Clinic in Rochester, Minnesota, Rochester
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
RecruitingPhase 1
- Mayo Clinic - Rochester, Rochester
A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
RecruitingPhase 2
- Mayo Clinic in Rochester, Minnesota, Rochester
Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies
RecruitingPhase 2
- Mayo Clinic, Rochester
A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations
RecruitingPhase 1/2
- Mayo Rochester, Rochester
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
RecruitingPhase 3
- Mayo Clinic, Rochester
A Study of LOXO-783 in Patients With Breast Cancer/Other Solid Tumors
RecruitingPhase 1
- Mayo Clinic, Rochester
Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration
RecruitingPhase 1/2
- Mayo Clinic, Rochester
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
RecruitingPhase 3
- Mayo Clinic in Rochester, Rochester
PRE-ISPY Phase I/II Oncology Platform Program
RecruitingPhase 1/2
- Mayo Clinic Comprehensive Cancer Center, Rochester
Phase Ib Study of Axatilimab in Combination With Olaparib in BRCA1/2 and PALB2- Associated Metastatic HER2-negative Breast Cancer
RecruitingPhase 1
- Mayo Clinic, Rochester
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
RecruitingPhase 3
- Mayo Clinic-Comprehensive Cancer Center-Breast Clinic, Rochester
Integrating Molecular Pathology, Radiology, and Genetics to Improve Breast Cancer Risk
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer
RecruitingPhase 2Healthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
A 3D-Printed External Breast Prosthesis for the Improvement of Patient-reported Outcomes Among Breast Cancer Patients That Underwent a Mastectomy Without Reconstruction
Recruiting
- Mayo Clinic in Rochester, Rochester
Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial
RecruitingPhase 3
- Mayo Clinic in Rochester, Rochester
E-Mindfulness Approaches for Living After Breast Cancer
RecruitingPhase 3
- Mayo Clinic in Rochester, Rochester
A Vaccine (MV-s-NAP) for the Treatment of Patients With Invasive Metastatic Breast Cancer
RecruitingPhase 1
- Mayo Clinic in Rochester, Rochester
Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers
RecruitingPhase 1
- Mayo Clinic Rochester, Rochester
A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer
RecruitingPhase 2
- Mayo Clinic, Rochester
A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors
RecruitingPhase 1/2
- Mayo Clinic - Rochester, Rochester
Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
RecruitingPhase 3
- Mayo Clinic - Rochester, Rochester
3D Ultrasound for the Imaging of Lymph Nodes in Patients With Breast Cancer
RecruitingEarly phase 1
- Mayo Clinic in Rochester, Rochester
Phase 1 Study of CLR 125 in Triple Negative Breast Cancer
RecruitingPhase 1
- Mayo Clinic Rochester, Rochester
3D Ultrasound Breast Imaging
Recruiting
- Mayo Clinic in Rochester, Rochester
The Sarah Nanotechnology System for Treatment of Advanced Metastatic Solid Tumors Using Hyperthermia.
Recruiting
- Mayo Clinic, Rochester
I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
RecruitingPhase 2
- Mayo Clinic, Rochester
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
RecruitingPhase 3
- Mayo Clinic in Rochester, Rochester
Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis
RecruitingPhase 1/2
- Mayo Clinic, Rochester
Collecting Patient-Reported Experiences With Radiation Dermatitis in Breast Cancer Patients Undergoing Radiotherapy
RecruitingObservational study
- Mayo Clinic in Rochester, Rochester
A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
RecruitingPhase 1/2
- Mayo Clinic, Rochester
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
RecruitingObservational study
- Mayo Clinic, Rochester
Development of Patient Derived Xenografts (PDX) in Patients With Breast Cancer
RecruitingObservational study
- Mayo Clinic, Rochester
Collection of Specimens and Clinical Data for Patients With Recurrent or Metastatic Breast Cancer or Male Breast Cancer
RecruitingObservational study
- Mayo Clinic in Rochester, Rochester
Quantitative Microvasculature Imaging for Breast Cancer Detection and Monitoring
RecruitingObservational study
- Mayo Clinic in Rochester, Rochester
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
Molecular Breast Imaging Guidance for Breast Biopsy for Patients With Breast Abnormalities
Recruiting
- Mayo Clinic in Rochester, Rochester
A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors
RecruitingPhase 1
- Exelixis Clinical Site #14, Rochester
Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of BTX-9341 in Advanced and/or Metastatic Breast Cancer
RecruitingPhase 1
- Biotheryx Investigative Site, Rochester
About Breast Cancer
Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.
More about Breast Cancer on MedlinePlus
Breast Cancer trials in other cities
- New York City, NY134 studies
- Houston, TX126 studies
- Boston, MA110 studies
- Nashville, TN79 studies
- Los Angeles, CA71 studies
- Edison, NJ69 studies
- St. Louis, MO65 studies
- Queens, NY63 studies
- Durham, NC63 studies
- Chicago, IL58 studies
- Philadelphia, PA56 studies
- Dallas, TX54 studies
Other studies in Rochester
- Non-Small Cell Lung Cancer38 studies
- Cancer (all types)31 studies
- Metastatic Cancer30 studies
- Colorectal Cancer29 studies
- Ovarian Cancer29 studies
- Multiple Myeloma23 studies
- Pancreatic Cancer23 studies
- Heart Failure22 studies
- Prostate Cancer22 studies
- Lung Cancer20 studies
- Endometrial Cancer19 studies
- Chronic Lymphocytic Leukemia19 studies
From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.