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Breast Cancer clinical trials in Rochester, MN
39 studies for Breast Cancer are looking for participants at sites in and around Rochester (within about 30 miles). Open a study to see who can join and how to contact the study team.
Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →
Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
RecruitingPhase 3
- Mayo Clinic - Rochester, Rochester
Trial of 225Ac-DOTATATE (RYZ101) in Subjects With ER+, HER2-negative Unresectable or Metastatic Breast Cancer Expressing SSTRs.
RecruitingPhase 1/2
- Research Facility, Rochester
ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer
RecruitingPhase 2
- Mayo Clinic Cancer Center, Rochester
Collecting Patient-Reported Experiences With Radiation Dermatitis in Breast Cancer Patients Undergoing Radiotherapy
RecruitingObservational study
- Mayo Clinic in Rochester, Rochester
Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
Recruiting
- Mayo Clinic, Rochester
Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration
RecruitingPhase 1/2
- Mayo Clinic, Rochester
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
RecruitingPhase 3
- Mayo Clinic in Rochester, Minnesota, Rochester
E-Mindfulness Approaches for Living After Breast Cancer
RecruitingPhase 3
- Mayo Clinic in Rochester, Rochester
A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
RecruitingPhase 2
- Mayo Clinic in Rochester, Minnesota, Rochester
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
RecruitingObservational study
- Mayo Clinic, Rochester
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
RecruitingPhase 1
- Mayo Clinic - Rochester, Rochester
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
RecruitingPhase 3
- Mayo Clinic in Rochester, Rochester
A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations
RecruitingPhase 1/2
- Mayo Rochester, Rochester
Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis
RecruitingPhase 1/2
- Mayo Clinic, Rochester
Phase 1 Study of CLR 125 in Triple Negative Breast Cancer
RecruitingPhase 1
- Mayo Clinic Rochester, Rochester
Molecular Breast Imaging Guidance for Breast Biopsy for Patients With Breast Abnormalities
Recruiting
- Mayo Clinic in Rochester, Rochester
A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer
RecruitingPhase 2
- Mayo Clinic, Rochester
Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer
RecruitingPhase 2Healthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
PRE-ISPY Phase I/II Oncology Platform Program
RecruitingPhase 1/2
- Mayo Clinic Comprehensive Cancer Center, Rochester
Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy
Recruiting
- Mayo Clinic, Rochester
Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies
RecruitingPhase 2
- Mayo Clinic, Rochester
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
RecruitingPhase 3
- Mayo Clinic-Comprehensive Cancer Center-Breast Clinic, Rochester
Phase Ib Study of Axatilimab in Combination With Olaparib in BRCA1/2 and PALB2- Associated Metastatic HER2-negative Breast Cancer
RecruitingPhase 1
- Mayo Clinic, Rochester
Integrating Molecular Pathology, Radiology, and Genetics to Improve Breast Cancer Risk
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
A 3D-Printed External Breast Prosthesis for the Improvement of Patient-reported Outcomes Among Breast Cancer Patients That Underwent a Mastectomy Without Reconstruction
Recruiting
- Mayo Clinic in Rochester, Rochester
Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial
RecruitingPhase 3
- Mayo Clinic in Rochester, Rochester
A Vaccine (MV-s-NAP) for the Treatment of Patients With Invasive Metastatic Breast Cancer
RecruitingPhase 1
- Mayo Clinic in Rochester, Rochester
Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers
RecruitingPhase 1
- Mayo Clinic Rochester, Rochester
A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors
RecruitingPhase 1/2
- Mayo Clinic - Rochester, Rochester
3D Ultrasound for the Imaging of Lymph Nodes in Patients With Breast Cancer
RecruitingEarly phase 1
- Mayo Clinic in Rochester, Rochester
3D Ultrasound Breast Imaging
Recruiting
- Mayo Clinic in Rochester, Rochester
The Sarah Nanotechnology System for Treatment of Advanced Metastatic Solid Tumors Using Hyperthermia.
Recruiting
- Mayo Clinic, Rochester
I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
RecruitingPhase 2
- Mayo Clinic, Rochester
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
RecruitingPhase 3
- Mayo Clinic in Rochester, Rochester
A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
RecruitingPhase 1/2
- Mayo Clinic, Rochester
Development of Patient Derived Xenografts (PDX) in Patients With Breast Cancer
RecruitingObservational study
- Mayo Clinic, Rochester
Collection of Specimens and Clinical Data for Patients With Recurrent or Metastatic Breast Cancer or Male Breast Cancer
RecruitingObservational study
- Mayo Clinic in Rochester, Rochester
Quantitative Microvasculature Imaging for Breast Cancer Detection and Monitoring
RecruitingObservational study
- Mayo Clinic in Rochester, Rochester
Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of BTX-9341 in Advanced and/or Metastatic Breast Cancer
RecruitingPhase 1
- Biotheryx Investigative Site, Rochester
About Breast Cancer
Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. Learn about the types, diagnosis, and treatments.
More about Breast Cancer on MedlinePlus
Breast Cancer trials in other cities
- New York City, NY144 studies
- Houston, TX126 studies
- Boston, MA110 studies
- Nashville, TN78 studies
- Los Angeles, CA73 studies
- Edison, NJ70 studies
- Queens, NY67 studies
- Durham, NC63 studies
- St. Louis, MO63 studies
- Chicago, IL59 studies
- Dallas, TX54 studies
- Philadelphia, PA51 studies
Other studies in Rochester
- Non-Small Cell Lung Cancer38 studies
- Cancer (all types)31 studies
- Metastatic Cancer28 studies
- Ovarian Cancer27 studies
- Colorectal Cancer27 studies
- Multiple Myeloma25 studies
- Heart Failure21 studies
- Lung Cancer21 studies
- Prostate Cancer20 studies
- Pancreatic Cancer20 studies
- Chronic Lymphocytic Leukemia20 studies
- Endometrial Cancer19 studies
From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.