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Lung Cancer clinical trials in Charleston, SC

11 studies for Lung Cancer are looking for participants at sites in and around Charleston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

RecruitingPhase 3
  • Ralph H Johnson VA Medical Center, Charleston
  • Medical University of South Carolina, Charleston
Ages 70 and older · All sexes · Updated Oct 5, 2026 · NCT06096844

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

RecruitingPhase 3
  • Bon Secours Saint Francis Hospital, Charleston
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT04267848

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

RecruitingPhase 3
  • Medical University of South Carolina-Hollings Cancer Center ( Site 0045), Charleston
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06312137

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

Health Education Approach to Lung Screening

RecruitingHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 50 to 80 · All sexes · Updated Aug 25, 2026 · NCT06070870

Prediction Augmented Screening Initiative

Recruiting
  • Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston
Ages 50 to 80 · All sexes · Updated Jun 26, 2026 · NCT06538636

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Ralph H Johnson VA Medical Center, Charleston
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05642572

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

RecruitingObservational study
  • Medical University of South Carolina (MUSC), Charleston
Ages 50 and older · All sexes · Updated Aug 5, 2025 · NCT06122077

Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier

RecruitingObservational study
  • Ralph H. Johnson VA Health Care System, Charleston
Ages 29 to 85 · All sexes · Updated Nov 13, 2024 · NCT06426628

About Lung Cancer

Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.

More about Lung Cancer on MedlinePlus

Lung Cancer trials in other cities

Other studies in Charleston

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.