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Opioid Overdose clinical trials in New York City, NY

12 studies for Opioid Overdose are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Adjunctive Cannabidiol for Recovery From Opioid Study

RecruitingPhase 3
  • Icahn School of Medicine at Mount Sinai, New York
Ages 18 to 65 · All sexes · Updated Oct 1, 2026 · NCT06940674

A Study of Brenipatide in Participants With Opioid Use Disorder

RecruitingPhase 2
  • Adams Clinical Harlem, New York
Ages 18 to 75 · All sexes · Updated Sep 22, 2026 · NCT07420283

GLP-1R Agonist Treatment for Opioid Use Disorder

RecruitingPhase 2
  • NYU Langone Health, New York
Ages 18 to 75 · All sexes · Updated Aug 28, 2026 · NCT06548490

Shelter HArm Reduction Evaluation

RecruitingObservational study
  • NYU Langone Health, New York
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07170072

Project I Test: Implementing HIV Testing in Opioid Treatment Programs

RecruitingHealthy volunteers welcome
  • Columbia University Medical Center, New York
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT03135886

Assessing Optimal XRB Initiation Points in Jail

RecruitingPhase 4
  • NYU Langone Health - 180 Madison Ave, New York
All ages · Men · Updated Aug 7, 2026 · NCT06051890

Exablate for LIFU Neuromodulation in Patients With Opioid Use Disorder (OUD) and/or Other Substance Use Disorders (SUDs)

RecruitingHealthy volunteers welcome
  • Weill Cornell Medicine, New York
Ages 18 to 60 · All sexes · Updated Jun 26, 2026 · NCT04197921

Smartphones for Opiate Addiction Recovery

RecruitingPhase 3
  • NYU Langone, New York
Ages 18 to 85 · All sexes · Updated Jun 23, 2026 · NCT05033028

A Clinical Trial Comparing Buprenorphine Formulations for High Potency Synthetic Opioid Use

RecruitingEarly phase 1
  • Substance Treatment and Research Service, New York
Ages 18 to 65 · All sexes · Updated Jun 2, 2026 · NCT06726200

Addressing Racial Disparities in Opioid Overdose Using Peer Recovery Coach Training and mHealth Platform

Recruiting
  • START Treatment and Recovery, New York
Ages 18 to 99 · All sexes · Updated May 27, 2026 · NCT06573476

E-Cigarettes for Harm Reduction in Smokers With Opioid Use Disorder

RecruitingPhase 2
  • NYU Langone Health, New York
Ages 21 to 75 · All sexes · Updated Mar 11, 2026 · NCT05722561

Psilocybin for Opioid Use Disorder (OUD)

RecruitingPhase 2
  • NYU Langone Health, New York
Ages 18 to 65 · All sexes · Updated Jan 23, 2026 · NCT06796062

About Opioid Overdose

Opioid overdose leads to slowing or stopping of breathing and sometimes death. You can take steps to help prevent an overdose, and respond to one with naloxone.

More about Opioid Overdose on MedlinePlus

Opioid Overdose trials in other cities

Other studies in New York City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.