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Opioid Overdose clinical trials in Baltimore, MD

18 studies for Opioid Overdose are looking for participants at sites in and around Baltimore (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder

RecruitingObservational studyHealthy volunteers welcome
  • National Institute on Drug Abuse, Baltimore
Ages 21 to 60 · All sexes · Updated Oct 2, 2026 · NCT03745339

A Study of Brenipatide in Participants With Opioid Use Disorder

RecruitingPhase 2
  • Maryland Treatment Centers - Mountain Manor Treatment Center, Baltimore
Ages 18 to 75 · All sexes · Updated Sep 22, 2026 · NCT07420283

Ketamine for Opioid Use Disorder

RecruitingPhase 2
  • University of Maryland Addiction Programs and Affiliated Clinics, Baltimore
Ages 18 to 65 · All sexes · Updated Aug 31, 2026 · NCT06943859

Evaluating Buspirone to Treat Opioid Withdrawal

RecruitingPhase 2
  • Kahlert Institute for Addictino Medicin, Baltimore
Ages 18 to 75 · All sexes · Updated Aug 24, 2026 · NCT05511909

Outpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder

RecruitingPhase 2
  • Johns Hopkins Center for Psychedelic and Consciousness Research, Baltimore
Ages 21 to 70 · All sexes · Updated Jul 17, 2026 · NCT06067737

Exablate for LIFU Neuromodulation in Patients With Opioid Use Disorder (OUD) and/or Other Substance Use Disorders (SUDs)

RecruitingHealthy volunteers welcome
  • University of Maryland, Baltimore, Baltimore
Ages 18 to 60 · All sexes · Updated Jun 26, 2026 · NCT04197921

Resilience Among Individuals With Opioid Use Disorder

Recruiting
  • Johns Hopkins University Bayview Medical Campus, Baltimore
  • Johns Hopkins University Bayview Medical Campus, Baltimore
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT06954402

Measuring Acute Drug Demand in Humans

RecruitingEarly phase 1Healthy volunteers welcome
  • General Clinical Research Center, Baltimore
Ages 18 to 65 · All sexes · Updated Jun 23, 2026 · NCT05829655

Buprenorphine for Individuals in Jail

RecruitingPhase 3Healthy volunteers welcome
  • Friends Research Institute, Baltimore
  • Baltimore Central Booking & Intake Center, Baltimore
Ages 18 and older · All sexes · Updated Jun 4, 2026 · NCT06306443

A Setting Focus Overdose Prevention Intervention

RecruitingHealthy volunteers welcome
  • Lighthouse Studies at Peer Point, Baltimore
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT05320835

Peer Recovery to Improve Polysubstance Use and Mobile Telemedicine Retention

Recruiting
  • University of Maryland Baltimore (UMD Drug Treatment Center), Baltimore
Ages 18 and older · All sexes · Updated Apr 27, 2026 · NCT05973838

Social Network Overdose Prevention and Education Intervention

Recruiting
  • Johns Hopkins Bloomberg School of Public Health, Baltimore
Ages 18 and older · All sexes · Updated Mar 4, 2026 · NCT06327061

Divided or Single Exposure (DOSE) Study

RecruitingPhase 2/3
  • Addiction Treatment Services (ATS), Baltimore
Ages 18 to 100 · All sexes · Updated Feb 3, 2026 · NCT05459402

Expanding the Youth Opioid Recovery Support (YORS) Intervention for MOUD Adherence to Adolescents With OUD

Recruiting
  • Maryland Treatment Centers, Baltimore
Ages 13 to 21 · All sexes · Updated Nov 18, 2025 · NCT06774248

Continuum of Care in Hospitalized Patients With Opioid/Stimulant Use Disorder and Infectious Complications From Drug Use

Recruiting
  • University of Maryland Baltimore, Baltimore
Ages 18 and older · All sexes · Updated Oct 31, 2025 · NCT06513156

The Youth Opioid Recovery Support (YORS) Intervention

Recruiting
  • Mountain Manor Treatment Center, Baltimore
Ages 18 to 28 · All sexes · Updated Sep 24, 2025 · NCT04173416

Assessing a Clinically-meaningful Opioid Withdrawal Phenotype

RecruitingPhase 2
  • University of Maryland, Baltimore
Ages 18 to 65 · All sexes · Updated Sep 12, 2025 · NCT05027919

EXPANDED SCOPE for Parent Grant Entitled, "Peer Recovery Support Services for Individuals in Recovery Residences on MOUD"

Recruiting
  • Maryland Treatment Centers, Baltimore
Ages 18 and older · All sexes · Updated Apr 4, 2025 · NCT06696157

About Opioid Overdose

Opioid overdose leads to slowing or stopping of breathing and sometimes death. You can take steps to help prevent an overdose, and respond to one with naloxone.

More about Opioid Overdose on MedlinePlus

Opioid Overdose trials in other cities

Other studies in Baltimore

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.