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Jump: MR Simulation For Radiation Therapy Master Protocol
Recruiting
Judging MR Simulation Procedures: A Phase I-II Study of the Use of Magnetic Resonance Imaging Simulation in the Planning of Radiation Treatments
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Participants must have a confirmed malignancy requiring radiation therapy. * Age: 18 years or older * ECOG performance status ≤2 (Karnofsky ≥60%, see Appendix A) * Ability to understand and the willingness to sign a written informed consent document. * Disease-specific eligibility criteria will be specified in the appropriate subprotocol. Exclusion Criteria: * For MRI involving contrast, history of allergic reactions attributed to gadolinium based IV contrast. Note: If patient will not receive contrast, this is not applicable * Participants who cannot undergo an MRI * Disease-specific exclusion criteria will be specified in the appropriate subprotocol
About the study
This is a master protocol for a prospective Phase I-II study evaluating feasibility and efficacy of incorporating magnetic resonance imaging (MRI) simulation into the planning of radiation treatments.
What is being tested
- MRI Simulator (device)
- Radiation Therapy (radiation)
Sponsor: Brigham and Women's Hospital · Participants: 86 · Started: Oct 14, 2020
Contact the study team
- Raymond Mak, MD · Phone: 617-632-5734
Official record on ClinicalTrials.gov — NCT04545957
Locations in the U.S.
| Massachusetts | Brigham and Women Hospital, Boston Dana Farber Cancer Institute, Boston |
Conditions
From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.