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Pre- and Post-operative TEG Indices in Patients With or Without Adenocarcinoma Undergoing Surgical Resection

RecruitingObservational studyHealthy volunteers welcome

Use of Viscoelastic Assays Beyond Coagulation: Pre- and Post-operative TEG

Who can join

Ages 18 to 99 · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* new diagnosis by the providing physician of hepatopancreaticobiliary, esophageal, colorectal, lung adenocarcinoma, or liver metastasis of any origin will be eligible for enrollment in the study
* 18 Years and older

Exclusion Criteria:

* Under 18 years old
* prisoners
* unable to provide informed consent
* pregnant women
* and those undergoing emergent or urgent operative intervention at the time of diagnosis

About the study

The investigators hypothesize that abnormalities in thromboelastography (TEG) parameters in patients with liver, pancreas, biliary, esophageal, colorectal, and lung adenocarcinoma can serve as biomarkers for oncologic disease burden, cancer recurrence and overall survival as well as thrombotic and hemorrhagic post-operative complications. The investigators further hypothesize that there is histologic pathology correlates to pre-operative TEG abnormalities, and that it identifies patients with virulent tumor biology.

What is being tested

Sponsor: University of Colorado, Denver · Participants: 200 · Started: Jun 26, 2022

Contact the study team

Official record on ClinicalTrials.gov — NCT05517811

Locations in the U.S.

ColoradoUniversity of Colorado Denver, Aurora
UCHealth Highlands Ranch Hospital, Highlands Ranch

Conditions

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.