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100-Year Human Aging Study
100-Year Human Aging Study: Prospective Longitudinal Validation of Multi-System Health Measurements Against Mortality and Aging Outcomes
Who can join
Ages 18 and older · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Age 18 years or older * Willing and able to provide written informed consent, or enrollment with consent of a legally authorized representative * Willing to participate in longitudinal follow-up Exclusion Criteria: * Age under 18 years
About the study
The 100-Year Human Aging Study is a prospective, pragmatic, observational trial enrolling participants across fixed clinical sites, mobile clinical sites, and an online participation pathway (current and future) to undergo comprehensive multi-system health screening and longitudinal follow-up until death. Participants are followed to determine whether measurements taken at enrollment and repeated across the lifespan - individually and in combination - predict all-cause mortality, cause-specific mortality, incident serious disease, and functional disability. The study is designed to generate the surrogate endpoint validation data that longevity medicine currently lacks.
What is being tested
- Comprehensive Multi-System Clinical Screening (diagnostic test)
Sponsor: Longevity Metrics, Inc. · Participants: 1,000,000 · Started: Feb 9, 2025
Contact the study team
- William E Brandenburg, MD · Phone: 3035010016
Official record on ClinicalTrials.gov — NCT07563777
Locations in the U.S.
| Colorado | Longevity Metrics, Boulder |
Conditions
From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.