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Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic Pain
RecruitingObservational study
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Diagnosis of chronic pain (generally pain duration of at least 3-6 months) localized to an anatomical region appropriate for cryoneurolysis as determined by the treating physician. * Planned cryoneurolysis procedure as part of standard clinical care. * Ability to provide written informed consent. * Ability and willingness to complete baseline and follow-up questionnaires. Exclusion Criteria: * Cryoneurolysis performed as part of a separate investigational trial in which data sharing is not permitted. * Active infection or other clinical contraindication to the procedure as determined by the treating clinician. * Life expectancy of less than 12 months in the judgment of the treating clinician. * Any condition that, in the investigator's opinion, would interfere with study participation or completion of follow-up, such as severe psychiatric instability or active substance use that precludes reliable follow-up
About the study
To prospectively describe patient-centered and health utilization outcomes through 12 months after cryoneurolysis performed as routine clinical care for chronic pain at Yale.
Sponsor: Yale University · Participants: 80 · Started: Jun 20, 2026
Contact the study team
- Charles A Odonkor, MD · Phone: 203-767-1555
Official record on ClinicalTrials.gov — NCT07639060
Locations in the U.S.
| Connecticut | Yale New Haven Health Old Saybrook Medical Center, Old Saybrook |
Conditions
- Chronic Pain
- Peripheral Nerve Disorders
- Hip Osteoarthritis
- Knee Osteoarthritis
- Muscle Spasticity
- Spondylosis
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.