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Health Ahead Comparative Effectiveness Study
Health Ahead: Sequential Comparative-Effectiveness Studies Toward Automated, Universally Deployable Preventive Health Screening
Who can join
Ages 18 and older · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Age 18 years or older * Willing and able to provide written informed consent, or enrollment with consent of a legally authorized representative * Willing to participate in longitudinal follow-up. Exclusion Criteria: \- Age under 18 years.
About the study
The Health Ahead Comparative Effectiveness Study is a pragmatic, parallel-arm interventional platform that systematically compares successive changes to preventive health screening on the path toward a fully automated screening system deployable in any environment, including the most isolated and resource-limited communities. Each change is isolated as a single variable against current practice, and every comparison is evaluated with a common set of engagement, behavior-change, experience, cost, and longitudinal outcome measures, so results accumulate on a consistent yardstick across the life of the platform.
The first comparison evaluates AI-assisted versus human-only interpretation ("reads") of screening data. Subsequent pre-planned comparisons, added by protocol amendment, evaluate static versus interactive personalized report delivery; mobile community versus fixed laboratory screening; and a hybrid medical-droid-plus-human delivery model versus human-only screening.
What is being tested
- AI-Assisted Screening Interpretation (AI Reads) (behavioral)
- Human-Only Screening Interpretation (behavioral)
Sponsor: William Brandenburg, MD · Participants: 1,000,000 · Started: Jun 9, 2026
Contact the study team
- William Brandenburg, MD · Phone: 13035010016
Official record on ClinicalTrials.gov — NCT07669168
Locations in the U.S.
| Colorado | Longevity Metrics, Boulder |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.