Music-4-MS to Improve Cognition in People Living With Multiple Sclerosis: A Feasibility Study

Recruiting

A Randomized Controlled Trial of Music-4-MS Compared to Music Listening to Improve Cognition in People Living With Multiple Sclerosis: A Feasibility Study

Who can join

Ages 18 to 80 · All sexes

Full eligibility criteria

Inclusion Criteria:

* Diagnosed with multiple sclerosis (relapsing remitting, secondary progressive, primary progressive)
* Diagnosed more than 6 months prior to starting study
* Self-reported cognitive impairment as assessed by having at leased 5 problems "sometimes" or more often on the Perceived Deficits Questionnaire
* Read, write, and understand English
* Access to internet

Exclusion Criteria:

* Diagnosed with another neurological condition that causes cognitive impairment
* MS exacerbation within the last 30 days
* Professional musician (primary source of income)

About the study

Multiple sclerosis (MS) rates in the U.S. have nearly doubled over the past decade, making it a leading cause of nontraumatic functional impairment in young adults and significantly affecting cognitive function in up to 70% of people with MS. While traditional cognitive rehabilitation methods are limited in sensory engagement, music training offers a multisensory approach that enhances neuroplasticity and improves cognitive functions. This study investigates the feasibility of Music-4-MS, a 12-week music-based eHealth intervention, to support cognitive and emotional health in individuals with MS.

What is being tested

Music Training Intervention (behavioral)
Music Listening (behavioral)

Sponsor: University of Texas at Austin · Participants: 64 · Started: Aug 10, 2026

Contact the study team

Carolyn Phillips, PhD, RN · Phone: 512-475-7039

Official record on ClinicalTrials.gov — NCT07759115

Locations in the U.S.

Texas

University of Texas at Austin, Austin

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.