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Atrial Fibrillation clinical trials recruiting in the U.S.
107 studies for Atrial Fibrillation are recruiting participants at sites across the United States.
Atrial fibrillation (AF or AFib) is the most common type of arrhythmia (irregular heartbeat). Read about symptoms and treatment.
Cities with the most studies
- New York City, NY21 studies
- Boston, MA17 studies
- Cleveland, OH17 studies
- Atlanta, GA16 studies
- Jonesboro, AR12 studies
- Philadelphia, PA12 studies
- Chicago, IL12 studies
- Ann Arbor, MI11 studies
- Columbus, OH10 studies
- Cincinnati, OH10 studies
- Pittsburgh, PA10 studies
- Austin, TX9 studies
- Los Angeles, CA9 studies
- Houston, TX9 studies
- Dallas, TX9 studies
- Indianapolis, IN9 studies
- Orlando, FL9 studies
- St. Louis, MO9 studies
- Queens, NY9 studies
- Washington, DC8 studies
- Aurora, CO8 studies
- Evanston, IL8 studies
- New Orleans, LA8 studies
- Overland Park, KS8 studies
- Birmingham, AL7 studies
- Salt Lake City, UT7 studies
- Oklahoma City, OK7 studies
- Miami, FL7 studies
- Sarasota, FL7 studies
- Tampa, FL7 studies
- Jacksonville, FL7 studies
- Ventura, CA7 studies
- Baltimore, MD7 studies
- San Francisco, CA7 studies
- The Bronx, NY7 studies
- San Diego, CA7 studies
- Huntington Beach, CA7 studies
- Durham, NC7 studies
- Louisville, KY6 studies
- Detroit, MI6 studies
By state
- Alabama11 studies
- Arizona10 studies
- Arkansas14 studies
- California30 studies
- Colorado12 studies
- Connecticut5 studies
- District of Columbia5 studies
- Florida22 studies
- Georgia17 studies
- Illinois22 studies
- Indiana12 studies
- Iowa8 studies
- Kansas11 studies
- Kentucky11 studies
- Louisiana12 studies
- Maine5 studies
- Maryland11 studies
- Massachusetts19 studies
- Michigan20 studies
- Minnesota9 studies
- Missouri12 studies
- Nebraska3 studies
- New Jersey10 studies
- New Mexico3 studies
- New York33 studies
- North Carolina15 studies
- Ohio30 studies
- Oklahoma8 studies
- Oregon4 studies
- Pennsylvania19 studies
- South Carolina8 studies
- South Dakota3 studies
- Tennessee12 studies
- Texas24 studies
- Utah10 studies
- Virginia15 studies
- Washington10 studies
- West Virginia3 studies
- Wisconsin8 studies
Recently updated studies
Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax
RecruitingObservational study
Ages 18 to 110 · All sexes · Updated Oct 2, 2026 · NCT05724121Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation
Recruiting
Ages 21 and older · All sexes · Updated Oct 2, 2026 · NCT07220525Digitally Rendered Interventions And Knowledge To Limit Ethanol-Associated Atrial Fibrillation Severity
Recruiting
Ages 21 and older · All sexes · Updated Oct 2, 2026 · NCT06995391Optimal Anti-Thrombotic Management Following Percutaneous Left Atrial Appendage Occlusion
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07840365The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation
RecruitingPhase 3
Ages 22 to 85 · All sexes · Updated Sep 30, 2026 · NCT05836987A Study Assessing Long-Term Safety and Effectiveness in Treatment Management of Atrial Fibrillation With VARIPULSE Catheter System
Recruiting
Ages 22 and older · All sexes · Updated Sep 30, 2026 · NCT07227532Comparing Magnesium 2g Versus 4g Versus Placebo in the Incidence of Treating AFF RVR
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06376916Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07626411Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07175428A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07217067A Study of VARIPULSE Catheter in Participants With Persistent Atrial Fibrillation Undergoing Pulmonary Vein and Superior Vena Cava Isolation
Recruiting
Ages 18 to 80 · All sexes · Updated Sep 25, 2026 · NCT07527299Evaluation of the FARAFLEX Mapping and Pulsed Field Ablation System in Subjects With Atrial Fibrillation
Recruiting
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT07575269Comparing the Safety and Efficacy of Apixaban and Rivaroxaban
RecruitingPhase 4
Ages 22 and older · All sexes · Updated Sep 23, 2026 · NCT06953726ReVeRA-301: Etripamil in Atrial Fibrillation Phase 3
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06716021Real-world Experience of Catheter Ablation for the Treatment of Arrhythmias
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT04088071PULSED AF Post-Approval Study
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06578104The Fourth Left Atrial Appendage Occlusion Study
Recruiting
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05963698Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07430956A Study of VARIPULSE Pulsed Field Ablation (PFA) Catheter and FARAWAVE PFA Catheter in the Treatment of Participants With Persistent Atrial Fibrillation
Recruiting
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07523750Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT00921986Post-ablation Alcohol Impacts Arrhythmia Recurrence, Quality of Life and Cognition in AF
Recruiting
Ages 18 to 85 · All sexes · Updated Sep 14, 2026 · NCT05510167Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT07436299CellFX® Nanosecond Pulsed Field Ablation (nsPFA)™ Cardiac Surgery Clamp System to Treat Atrial Fibrillation
Recruiting
Ages 18 to 85 · All sexes · Updated Sep 9, 2026 · NCT06959121High-resolution MRI of Atrial Fibrillation Patients Prior to Focal Impulse and Rotor Modulation (FIRM) Ablation
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT03444337A Study to Test How Well BAY 3670549 Works and How Safe it is in Patients With Atrial Fibrillation
RecruitingPhase 2
Ages 18 to 85 · All sexes · Updated Sep 9, 2026 · NCT07625215From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.