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Crohn's Disease clinical trials in Ohio

30 studies for Crohn's Disease are looking for participants at sites in Ohio.

Cities in Ohio

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

  • Great Lakes Gastroenterology Research, LLC ( Site 5016), Mentor
RecruitingPhase 3
Ages 16 to 80 · All sexes · Updated Oct 2, 2026 · NCT06430801

Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis

  • Gastro Intestinal Research Institute of Northern Ohio /ID# 283860, Westlake
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Oct 2, 2026 · NCT07697456

Investigating the Effect of the Non-nutritive Sweetener Sucralose in Inflammatory Bowel Disease

  • UH Minoff Health Center, Chagrin Falls
  • University Hospitals Cleveland Medical Center, Cleveland
  • UH Westlake Health Center, Westlake
RecruitingHealthy volunteers welcome
Ages 18 to 75 · All sexes · Updated Oct 1, 2026 · NCT07852273

A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting

  • Gastro Health Research - Cincinnati, Cincinnati
  • DSI Research Northridge LLC, Dayton
  • Gastro Health Research - Liberty Township, Liberty Township
  • and 3 more
RecruitingPhase 4
Ages 18 to 80 · All sexes · Updated Sep 30, 2026 · NCT06581328

Non-nutritive Sweeteners in Inflammatory Bowel Disease

  • UH Minoff Health Center, Chagrin Falls
  • University Hospitals Cleveland Medical Center, Cleveland
  • UH Westlake Health Center, Westlake
RecruitingHealthy volunteers welcome
Ages 18 to 70 · All sexes · Updated Sep 25, 2026 · NCT07769437

Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

  • University of Cincinnati /ID# 265589, Cincinnati
  • The Ohio State University /ID# 265577, Columbus
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 25, 2026 · NCT06548542

A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease

  • Great Lakes Gastroenterology Research, LLC, Mentor
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07499232

A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants

  • Cincinnati Children's Hospital Medical Center, Cincinnati
RecruitingPhase 3
Ages 3 and older · All sexes · Updated Sep 25, 2026 · NCT06663332

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

  • Great Lakes Gastroenterology Research, LLC, Mentor
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 25, 2026 · NCT06233461

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

  • Gastro Intestinal Research Institute of Northern Ohio, LLC, Westlake
RecruitingPhase 3
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937099

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

  • Ohio State University Comprehensive Cancer Center, Columbus
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT03816345

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

  • Gastroenterology & Hepatology Specialists, Inc.-Site nUmber: 8400139, Canton
  • University Hospitals Cleveland Medical Center-Site Number: 8400073, Cleveland
  • Ohio Gastroenterology Group Inc.-8400006, Columbus
  • and 5 more
RecruitingPhase 3
Ages 16 to 80 · All sexes · Updated Sep 23, 2026 · NCT07184931

A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

  • Ohio Gastroenterology Group Inc.-Site Number: 8400006, Columbus
  • Medical Associates Research Group-Site Number: 8400063, Columbus
  • OSU Wexner Medical Center-Site Number: 8400077, Columbus
  • and 1 more
RecruitingPhase 3
Ages 16 to 80 · All sexes · Updated Sep 23, 2026 · NCT07184944

A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

  • University of Cincinnati, Cincinnati
  • Ohio Gastroenterology group, Inc., Columbus
  • Great Lakes Gastroenterology Research, LLC, Mentor
  • and 1 more
RecruitingPhase 4
Ages 18 to 70 · All sexes · Updated Sep 9, 2026 · NCT06045754

A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease

  • Great Lakes Gastroenterology Research, LLC, Mentor
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07577843

Ultrasound-Guided Versus Standard Margin Selection in Ileocecal Resection of Terminal Ileal CD

  • Cleveland Clinic, Cleveland
Recruiting
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT07680283

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease

  • Childrens Medical Center, Dayton
RecruitingPhase 3
Ages 2 to 17 · All sexes · Updated Aug 24, 2026 · NCT05509777

Zymfentra (Infliximab-dyyb) REal World Cohort STudy

  • University of Cincinnati, Cincinnati
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07237516

Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

  • UH Cleveland Medical Center /ID# 262188, Cleveland
RecruitingPhase 3
Ages 2 to 17 · All sexes · Updated Jun 24, 2026 · NCT06332534

A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)

  • University Children's Clinic, Cleveland
  • Cleveland Clinic, Cleveland
RecruitingPhase 3
Ages 2 to 17 · All sexes · Updated Jun 22, 2026 · NCT06405087

Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease

  • Cincinnati Children's Hospital Medical Center, Cincinnati
  • UH/Rainbow Babies and Children's Hospital, Cleveland
  • Nationwide Children's Hospital, Columbus
RecruitingPhase 4
Ages 6 to 17 · All sexes · Updated May 27, 2026 · NCT05781152

A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

  • University Hospitals Cleveland Medical Center - 11100 Euclid Ave, Cleveland
RecruitingPhase 3
Ages 2 and older · All sexes · Updated May 7, 2026 · NCT05442567

Precise Infliximab Exposure and Pharmacodynamic Control

  • Cincinnati Children's Hospital, Cincinnati
  • Cleveland Clinic Children's Hospital, Cleveland
  • Nationwide Children's Hospital, Columbus
RecruitingPhase 2/3
Ages 6 to 22 · All sexes · Updated May 5, 2026 · NCT05660746

A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)

  • University Hospitals Cleveland Medical Center, Cleveland
RecruitingPhase 3
Ages 2 to 17 · All sexes · Updated May 5, 2026 · NCT04779320

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

  • OSU Inflammatory Bowel Disease Center, Hilliard
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Apr 27, 2026 · NCT06456593

A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease

  • Mirador Therapeutics Selected Site, Cincinnati
  • Mirador Therapeutics Selected Site, Liberty Township
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Mar 12, 2026 · NCT07113522

Treatment of Moderate to Severe Refractory Crohn's Disease

  • Cleveland Clinic, Cleveland
RecruitingPhase 1/2
Ages 18 to 65 · All sexes · Updated Dec 10, 2025 · NCT06721962

Evaluation of the SMART IBD App in Pediatric IBD

  • Cincinnati Children's Hospital Medical Center, Cincinnati
Recruiting
Ages 13 to 17 · All sexes · Updated Nov 21, 2025 · NCT07195123

Development of a Novel Endoscopic Index and Patient-reported Outcome Measure for Clinical Trials in Participants With Permanent Ileostomy

  • Cleveland Clinic Foundation, Cleveland
RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 12, 2025 · NCT06670638

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.