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Crohn's Disease clinical trials in Columbus, OH

7 studies for Crohn's Disease are looking for participants at sites in and around Columbus (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

RecruitingPhase 1
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT03816345

A Study of SL-325 in Crohn's Disease Patients

RecruitingPhase 2
  • Clinical Trial Site, Columbus
Ages 18 to 80 · All sexes · Updated Nov 12, 2026 · NCT07753850

A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 3
  • Ohio Gastroenterology Group Inc.-Site Number: 8400006, Columbus
  • Medical Associates Research Group-Site Number: 8400063, Columbus
  • OSU Wexner Medical Center-Site Number: 8400077, Columbus
Ages 16 to 80 · All sexes · Updated Oct 21, 2026 · NCT07184944

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 3
  • Ohio Gastroenterology Group Inc.-8400006, Columbus
  • OSU Wexner Medical Center-Site Number: 8400077, Columbus
Ages 16 to 80 · All sexes · Updated Oct 21, 2026 · NCT07184931

Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

RecruitingPhase 2
  • The Ohio State University /ID# 265577, Columbus
Ages 18 to 75 · All sexes · Updated Sep 25, 2026 · NCT06548542

Precise Infliximab Exposure and Pharmacodynamic Control

RecruitingPhase 2/3
  • Nationwide Children's Hospital, Columbus
Ages 6 to 22 · All sexes · Updated May 5, 2026 · NCT05660746

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

RecruitingPhase 2
  • OSU Inflammatory Bowel Disease Center, Hilliard · 10 mi away
Ages 18 to 75 · All sexes · Updated Apr 27, 2026 · NCT06456593

About Crohn's Disease

Crohn's Disease can cause inflammation in any area from the mouth to the anus. Read about medicines, surgery or dietary management to treat symptoms.

More about Crohn's Disease on MedlinePlus

Crohn's Disease trials in other cities

Other studies in Columbus

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.