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Down Syndrome clinical trials in North Carolina

8 studies for Down Syndrome are looking for participants at sites in North Carolina.

Cities in North Carolina

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

  • Mission Hospital, Asheville
  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill
  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • and 3 more
RecruitingPhase 2
Ages 1 to 30 · All sexes · Updated Sep 1, 2026 · NCT04546399

A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill
  • Wake Forest University Health Sciences, Winston-Salem
RecruitingObservational study
Ages 6 to 39 · All sexes · Updated Aug 25, 2026 · NCT05702645

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

  • Duke University Health System, Durham
RecruitingObservational studyHealthy volunteers welcome
Ages 0 to 20 · All sexes · Updated Aug 21, 2026 · NCT04278404

A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

  • Flourish Research, Matthews
RecruitingPhase 1/2
Ages 35 to 85 · All sexes · Updated Jul 10, 2026 · NCT05462106

Collaboration for Down Syndrome Progress (CDP)

  • University of North Carolina at Chapel Hill, Chapel Hill
RecruitingObservational study
All ages · All sexes · Updated Jun 4, 2026 · NCT07625579

Physical Activity and Community EmPOWERment Project

  • University of North Carolina, Chapel Hill
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Feb 23, 2026 · NCT06740162

Retinal Imaging in Neurodegenerative Disease

  • Duke University Medical Center, Durham
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Feb 4, 2026 · NCT03233646

Compassionate Use Study of Epi-ON Corneal Collagen Crosslinking Performed Using UVA Exposure on Eyes With Ectatic Corneal Diseases for Subjects With Down Syndrome

  • Woolfson Eye Institute, Asheville
RecruitingPhase 3
Ages 8 and older · All sexes · Updated Feb 2, 2026 · NCT07135167

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.