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Down Syndrome clinical trials in Durham, NC

6 studies for Down Syndrome are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

RecruitingPhase 2
  • Duke University Medical Center, Durham
  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Ages 1 to 30 · All sexes · Updated Sep 1, 2026 · NCT04546399

A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

RecruitingObservational study
  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Ages 6 to 39 · All sexes · Updated Aug 25, 2026 · NCT05702645

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

RecruitingObservational studyHealthy volunteers welcome
  • Duke University Health System, Durham
Ages 0 to 20 · All sexes · Updated Aug 21, 2026 · NCT04278404

Collaboration for Down Syndrome Progress (CDP)

RecruitingObservational study
  • University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
All ages · All sexes · Updated Jun 4, 2026 · NCT07625579

Physical Activity and Community EmPOWERment Project

RecruitingHealthy volunteers welcome
  • University of North Carolina, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Feb 23, 2026 · NCT06740162

Retinal Imaging in Neurodegenerative Disease

RecruitingObservational studyHealthy volunteers welcome
  • Duke University Medical Center, Durham
Ages 18 and older · All sexes · Updated Feb 4, 2026 · NCT03233646

About Down Syndrome

About 1 in 700 babies are born with the birth defect known as Down Syndrome. Learn about the different Down Syndrome types and related health issues.

More about Down Syndrome on MedlinePlus

Down Syndrome trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.