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Epilepsy clinical trials in Ohio

17 studies for Epilepsy are looking for participants at sites in Ohio.

Cities in Ohio

Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study

  • Cincinnati Children's Hospital Medical Center, Cincinnati
RecruitingPhase 2
1 Day – 6 Months · All sexes · Updated Oct 2, 2026 · NCT05104983

Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures FOCUS-1

  • Cleveland Clinic, Cleveland
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Oct 1, 2026 · NCT07563881

Prospective Natural History Study of POLG Disease

  • Akron Children's Hospital, Akron
RecruitingObservational study
All ages · All sexes · Updated Sep 15, 2026 · NCT07775872

Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up

  • University Hospitals Cleveland Medical Center, Cleveland
RecruitingObservational study
Ages 18 to 75 · All sexes · Updated Sep 15, 2026 · NCT07110454

Diagnosing Epilepsy To EffeCT Change

  • University Hospitals Cleveland Medical Center, Clevland
Recruiting
Ages 18 to 75 · All sexes · Updated Sep 15, 2026 · NCT07110337

AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy

  • Cleveland Clinic, Cleveland
  • Ohio State University, Columbus
RecruitingPhase 1/2
Ages 18 to 75 · All sexes · Updated Aug 24, 2026 · NCT06063850

A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

  • Summa Health Clinical Research Center, Akron
  • Cleveland Clinic Foundation, Cleveland
  • The Ohio State University, Columbus
  • and 1 more
RecruitingPhase 3
Ages 12 and older · All sexes · Updated Aug 10, 2026 · NCT05667142

Comparative Effectiveness of Palliative Surgery Versus Additional Anti-Seizure Medications for Lennox-Gastaut Syndrome

  • Nationwide Children's, Columbus
RecruitingObservational study
Up to age 26 · All sexes · Updated Aug 6, 2026 · NCT05374824

A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety

  • Praxis Research Site, Cincinnati
RecruitingPhase 3
1 Day – 18 Years · All sexes · Updated Aug 3, 2026 · NCT07019922

Epilepsy Journey-An Executive Functioning Intervention for Teens With Epilepsy

  • Cincinnati Children's Hospital Medical Center, Cincinnati
Recruiting
Ages 13 to 17 · All sexes · Updated Jun 25, 2026 · NCT06608966

Readiness Brain Operation Optimization Training (ReBOOT) for Epilepsy Surgery

  • Cleveland Clinic, Cleveland
Recruiting
Ages 18 to 60 · All sexes · Updated Jun 18, 2026 · NCT05992402

Healthy Aging in People With Epilepsy Program

  • Cleveland Clinic, Cleveland
RecruitingHealthy volunteers welcome
Ages 55 to 90 · All sexes · Updated Jun 12, 2026 · NCT06052605

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)

  • Cleveland Clinic, Cleveland
  • OhioHealth, Columbus
RecruitingPhase 3
Ages 18 and older · All sexes · Updated May 14, 2026 · NCT05716100

An Examination of Whether Infrared Light Therapy Can Reduce Stress in People With Epilepsy

  • Right Mind Wellness Center, Cincinnati
  • Holly Maggiano, MD, Warren
Recruiting
Ages 18 and older · All sexes · Updated Apr 23, 2026 · NCT07509177

Bridging the Gap: Educating Patients on Social Determinants of Health to Improve Epilepsy Surgery Access and Outcomes

  • Cleveland Clinic, Cleveland
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Apr 3, 2026 · NCT07509190

A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures

  • Cleveland Clinic Foundation, Cleveland
RecruitingPhase 2
Ages 18 to 70 · All sexes · Updated Jan 23, 2026 · NCT07219407

Epilepsy Learning Healthcare System (ELHS)

  • Akron Children's Hospital, Akron
  • Cincinnati Children's Hospital Comprehensive Epilepsy Center (CCHMC), Cincinnati
  • University of Cincinnati Gardner Neuroscience Institute Epilepsy Center, Cincinnati
RecruitingObservational study
All ages · All sexes · Updated Aug 30, 2024 · NCT06265103

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.