Lupus clinical trials in North Carolina
20 studies for Lupus are looking for participants at sites in North Carolina.
Cities in North Carolina
A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus
- Sl0044 50238, Charlotte
RecruitingPhase 3
Ages 16 and older · All sexes · Updated Oct 2, 2026 · NCT06617325A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)
- DJL Clinical Research, PLLC, Charlotte
- Cross Creek Medical Clinic, PA, Fayetteville
RecruitingPhase 2
Ages 18 to 74 · All sexes · Updated Oct 1, 2026 · NCT07409181An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants
- Research Site, Durham
RecruitingPhase 3
Ages 5 to 17 · All sexes · Updated Sep 30, 2026 · NCT05835310A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus
- Joint and Muscle Research Institute, Charlotte
- DJL Clinical Research, PLLC, Charlotte
- Cross Creek Medical Clinic, Fayetteville
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Sep 25, 2026 · NCT07438496Anifrolumab Pregnancy Study
- Research Site, Cary
RecruitingObservational study
Ages 18 to 130 · Women · Updated Sep 18, 2026 · NCT07049653A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.
- Research Site, Chapel Hill
RecruitingPhase 1
Ages 18 to 70 · All sexes · Updated Sep 15, 2026 · NCT06916806A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)
- Arthritis and Osteoporosis Consultants of the Carolinas II, LLC, Charlotte
- Superior Clinical Research, LLC, Smithfield
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Sep 14, 2026 · NCT07355218A Phase 2, Open-Label, Single-Arm Trial of FT819 in Participants With Lupus Nephritis
- Cross Creek Medical Clinic, Fayetteville
RecruitingPhase 2
Ages 12 to 70 · All sexes · Updated Sep 14, 2026 · NCT07570862A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE
- Research Site, Chapel Hill
- Research Site, Charlotte
RecruitingPhase 1/2
Ages 18 to 70 · All sexes · Updated Sep 10, 2026 · NCT06897930A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease
- Atrium Health Rheumatology-Southpark, Charlotte
- Duke University Medical Center, Durham
RecruitingPhase 1
Ages 18 to 74 · All sexes · Updated Sep 10, 2026 · NCT07085104A Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 Immunosuppressants
- DJL Clinical Research, PLLC, Charlotte
RecruitingObservational study
Ages 16 and older · All sexes · Updated Sep 3, 2026 · NCT07175285Prospective Registry Investigating Maternal and Infant Outcomes in Anifrolumab Users
- Research Site, Wilmington
RecruitingObservational study
All ages · Women · Updated Sep 2, 2026 · NCT06659029A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease
- University of North Carolina TraCS Institute - CTRC, Chapel Hill
RecruitingPhase 1
Ages 18 to 70 · All sexes · Updated Aug 28, 2026 · NCT06925542RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus
- UNC Chapel Hill, Chapel Hill
RecruitingPhase 1/2
Ages 18 to 65 · All sexes · Updated Aug 26, 2026 · NCT06121297Intervention to Improve Communication and Medication Adherence in Lupus
- Duke University, Durham
Recruiting
Ages 18 to 90 · All sexes · Updated Aug 17, 2026 · NCT06458075A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases
- Duke University, Durham
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT07115745A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease
- Duke University Health System, Durham
RecruitingPhase 1
Ages 12 to 70 · All sexes · Updated May 22, 2026 · NCT06308978Lupus Landmark Study: A Prospective Registry and Biorepository
- UNC Chapel Hill, Chapel Hill
RecruitingObservational study
Ages 18 to 110 · All sexes · Updated Apr 15, 2026 · NCT05934149Duke Lupus Registry
- Duke University Medical Center, Durham
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jan 8, 2026 · NCT00512694Maternal Autoimmune Disease Research Alliance (MADRA) Registry
- Duke University, Durham
RecruitingObservational studyHealthy volunteers welcome
All ages · Women · Updated Jan 8, 2026 · NCT03276923From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.