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Lupus clinical trials in Durham, NC

12 studies for Lupus are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

RecruitingPhase 3
  • Research Site, Durham
Ages 5 to 17 · All sexes · Updated Sep 30, 2026 · NCT05835310

A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE

RecruitingPhase 1/2
  • Research Site, Chapel Hill · 10 mi away
Ages 18 to 70 · All sexes · Updated Sep 10, 2026 · NCT06897930

A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

RecruitingPhase 1
  • Duke University Medical Center, Durham
Ages 18 to 74 · All sexes · Updated Sep 10, 2026 · NCT07085104

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

RecruitingPhase 1
  • University of North Carolina TraCS Institute - CTRC, Chapel Hill · 10 mi away
Ages 18 to 70 · All sexes · Updated Aug 28, 2026 · NCT06925542

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

RecruitingPhase 1/2
  • UNC Chapel Hill, Chapel Hill · 10 mi away
Ages 18 to 65 · All sexes · Updated Aug 26, 2026 · NCT06121297

Intervention to Improve Communication and Medication Adherence in Lupus

Recruiting
  • Duke University, Durham
Ages 18 to 90 · All sexes · Updated Aug 17, 2026 · NCT06458075

A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases

RecruitingPhase 1
  • Duke University, Durham
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT07115745

A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease

RecruitingPhase 1
  • Duke University Health System, Durham
Ages 12 to 70 · All sexes · Updated May 22, 2026 · NCT06308978

Lupus Landmark Study: A Prospective Registry and Biorepository

RecruitingObservational study
  • UNC Chapel Hill, Chapel Hill · 10 mi away
Ages 18 to 110 · All sexes · Updated Apr 15, 2026 · NCT05934149

Duke Lupus Registry

RecruitingObservational study
  • Duke University Medical Center, Durham
Ages 18 and older · All sexes · Updated Jan 8, 2026 · NCT00512694

Maternal Autoimmune Disease Research Alliance (MADRA) Registry

RecruitingObservational studyHealthy volunteers welcome
  • Duke University, Durham
All ages · Women · Updated Jan 8, 2026 · NCT03276923

About Lupus

Lupus is an autoimmune disease that causes your immune system to attack your healthy tissues and cells. This can cause damage to many parts of your body.

More about Lupus on MedlinePlus

Lupus trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.