Home › Melanoma › Illinois
Melanoma clinical trials in Illinois
22 studies for Melanoma are looking for participants at sites in Illinois.
Cities in Illinois
- Chicago15 studies
- Evanston8 studies
- Cicero7 studies
- Aurora7 studies
- Peoria6 studies
- Champaign6 studies
- Decatur5 studies
- Danville5 studies
- Springfield5 studies
- Waukegan5 studies
- Bloomington5 studies
- Naperville5 studies
- North Peoria4 studies
- Charleston4 studies
- Galesburg4 studies
- Carbondale3 studies
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
- OSF Saint Anthony's Health Center, Alton
- Rush-Copley Medical Center, Aurora
- Advocate Outpatient Center - Aurora, Aurora
- and 54 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
- University of Illinois Cancer Center, Chicago
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478DESTINY-PANTUMOUR04
- Research Site, Decatur
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study
- Rush-Copley Medical Center, Aurora
- Illinois CancerCare-Bloomington, Bloomington
- Illinois CancerCare-Canton, Canton
- and 38 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05136196A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
- Hope and Healing Cancer Services, Hinsdale
- Advocate Lutheran General Hospital, Park Ridge
- Illinois CancerCare, Peoria
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06246916Pan-tumor MRD Study
- Cancer Care Specialists of Illinois (CCSI), O'Fallon
- Carle Health, Urbana
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06605404Comparing the Effectiveness of Less Invasive Procedures With the Current Standard of Care for the Treatment of Older Adults With Early-Stage Melanoma
- Loyola Center for Health at Burr Ridge, Burr Ridge
- Northwestern University, Chicago
- Swedish Covenant Hospital, Chicago
- and 8 more
RecruitingPhase 3
Ages 75 and older · All sexes · Updated Sep 24, 2026 · NCT07068074A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases
- Saint Anthony's Health, Alton
- Rush - Copley Medical Center, Aurora
- Illinois CancerCare-Bloomington, Bloomington
- and 33 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04511013Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer
- Northwestern University, Chicago
- Memorial Hospital East, Shiloh
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT05896839Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
- Lurie Children's Hospital-Chicago, Chicago
RecruitingPhase 1/2
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119Project: Every Child for Younger Patients With Cancer
- Rush-Copley Medical Center, Aurora
- Lurie Children's Hospital-Chicago, Chicago
- Northwestern University, Chicago
- and 16 more
RecruitingObservational study
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
- Orchard Healthcare Research Inc, Skokie
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06330064Sun Exposure and Activities After Skin Cancer: Optimization of mHealth Interventions
- Northwestern University, Chicago
Recruiting
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT07556380A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)
- Call for Information (Investigational Site 0024), Chicago
RecruitingPhase 1/2
6 Months – 17 Years · All sexes · Updated Jul 6, 2026 · NCT02332668Integrated Cancer Repository for Cancer Research
- Rush-Copley Cancer Care Center, Aurora
- Rush-Copley Healthcare Center, Yorkville
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors
- University of Chicago Medical Center, Chicago
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated May 13, 2026 · NCT03686124A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body
- University of Chicago, Chicago
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Apr 28, 2026 · NCT06413680A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma
- Northwestern Memorial Hospital, Chicago
- University of Chicago Medical Center, Chicago
RecruitingPhase 2/3
All ages · All sexes · Updated Apr 2, 2026 · NCT06581406Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
- OSF Saint Anthony's Health Center, Alton
- Rush-Copley Medical Center, Aurora
- Advocate Outpatient Center - Aurora, Aurora
- and 45 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
- Massive Bio SYNERGY-AI site, Chicago
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
- Advocate Illinois Masonic Medical Center, Chicago
- Northwestern Medicine Cancer Center Kishwaukee, DeKalb
- Northwestern University, Evanston
- and 4 more
Recruiting
Ages 18 and older · All sexes · Updated Nov 27, 2024 · NCT03860883Adoptive T Cell Immunotherapy for Advanced Melanoma Using Engineered Lymphocytes
- Loyola University Medical Center, Maywood
RecruitingPhase 1
Ages 18 to 89 · All sexes · Updated Mar 12, 2018 · NCT02870244From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.