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Melanoma clinical trials in Springfield, IL

5 studies for Melanoma are looking for participants at sites in and around Springfield (within about 30 miles). Open a study to see who can join and how to contact the study team.

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

RecruitingPhase 2
  • Southern Illinois University School of Medicine, Springfield
  • Springfield Clinic, Springfield
  • Springfield Memorial Hospital, Springfield
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05136196

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

RecruitingPhase 2
  • Southern Illinois University School of Medicine, Springfield
  • Springfield Clinic, Springfield
  • Memorial Medical Center, Springfield
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04511013

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Southern Illinois University School of Medicine, Springfield
  • Springfield Clinic, Springfield
  • Springfield Memorial Hospital, Springfield
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

Project: Every Child for Younger Patients With Cancer

RecruitingObservational study
  • Saint John's Hospital, Springfield
  • Southern Illinois University School of Medicine, Springfield
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Southern Illinois University School of Medicine, Springfield
  • Springfield Clinic, Springfield
  • Springfield Memorial Hospital, Springfield
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

About Melanoma

Melanoma is the most serious type of skin cancer. Most have a black or black-blue area. Learn the 'ABCDE' of what to watch for and treatment options.

More about Melanoma on MedlinePlus

Melanoma trials in other cities

Other studies in Springfield

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.