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Prostate Cancer clinical trials in Minnesota

48 studies for Prostate Cancer are looking for participants at sites in Minnesota.

Cities in Minnesota

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

  • Sanford Joe Lueken Cancer Center, Bemidji
  • Coborn Cancer Center at Saint Cloud Hospital, Saint Cloud
RecruitingPhase 3
Ages 18 and older · Men · Updated Oct 2, 2026 · NCT06931340

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

  • Coborn Cancer Center at Saint Cloud Hospital, Saint Cloud
RecruitingPhase 3
Ages 18 and older · Men · Updated Oct 2, 2026 · NCT07200830

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • Riverwood Healthcare Center, Aitkin
  • Mayo Clinic Health System in Albert Lea, Albert Lea
  • Essentia Health - Baxter Clinic, Baxter
  • and 48 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

  • Essentia Health Saint Joseph's Medical Center, Brainerd
  • Essentia Health Cancer Center, Duluth
  • Coborn Cancer Center at Saint Cloud Hospital, Saint Cloud
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06632977

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

  • Health Partners Frauenshuh Cancer Center, Saint Louis Park
  • Health Partners Cancer Center at Regions Hospital, Saint Paul
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

  • Essentia Health - Deer River Clinic, Deer River
  • Essentia Health Cancer Center, Duluth
  • Fairview Southdale Hospital, Edina
  • and 8 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancer

  • University Of Minnesota, Minneapolis
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 28, 2026 · NCT06095089

Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer

  • M Health Fairview Clinics and Surgery Center, Minneapolis
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06801236

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

  • Avera Cancer Institute - Marshall ( Site 0122), Marshall
  • HealthPartners Cancer Research Center-HealthPartners Frauenshuh Cancer Center ( Site 0072), Saint Louis Park
  • HealthPartners Cancer Research Center-HealthPartners Cancer Center at Regions Hospital ( Site 0092), Saint Paul
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06136650

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

  • Minnesota Oncology Hematology PA, Minneapolis
  • University of Minnesota Medical Center Fairview, Minneapolis
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 22, 2026 · NCT07213674

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

  • Research Site, Rochester
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 18, 2026 · NCT06952803

Study of PSMA-targeted Therapy and Androgen Receptor Suppression in Low-volume Metastatic ProstatE Cancer: SPARKLE Trial

  • Mayo Clinic in Rochester, Rochester
RecruitingPhase 2
Ages 18 and older · Men · Updated Sep 18, 2026 · NCT07650240

A Study of GSK5458514 Administered Alone or In Combination With Other Anti-Cancer Agents in Participants With Prostate Cancer

  • GSK Investigational Site, Rochester
RecruitingPhase 1/2
Ages 18 and older · Men · Updated Sep 18, 2026 · NCT06990880

Carboplatin or Olaparib for BRcA Deficient Prostate Cancer

  • Minneapolis VA Health Care System, Minneapolis, MN, Minneapolis
RecruitingPhase 2
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT04038502

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

  • Mayo Clinic in Rochester, Minnesota-Mayo Clinic Comprehensive Cancer Center ( Site 0078), Rochester
  • HealthPartners Cancer Research Center-HealthPartners Frauenshuh Cancer Center ( Site 0032), Saint Louis Park
  • HealthPartners Cancer Center at Regions Hospital ( Site 0052), Saint Paul
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT06925737

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

  • Mayo Clinic, Rochester
Recruiting
Ages 18 and older · Men · Updated Sep 14, 2026 · NCT06511141

Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

  • Mayo Clinic- Rochester, Rochester
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 11, 2026 · NCT06056830

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

  • Sanford Joe Lueken Cancer Center, Bemidji
  • Essentia Health Saint Joseph's Medical Center, Brainerd
  • Minnesota Oncology Hematology PA-Chaska, Chaska
  • and 16 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05946213

The Vanguard Study: Testing a New Way to Screen for Cancer

  • Minneapolis VA Medical Center, Minneapolis
RecruitingHealthy volunteers welcome
Ages 45 to 75 · All sexes · Updated Sep 2, 2026 · NCT06995898

Phase Ib/II Platform Study of Multiple Anti-Cancer Agents in Participants With Metastatic Prostate Cancer

  • Research Site, Minneapolis
RecruitingPhase 1/2
Ages 18 to 99 · Men · Updated Aug 27, 2026 · NCT07590934

A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone Acetate or Darolutamide

  • Masonic Cancer Center, Minneapolis
RecruitingPhase 2
Ages 18 and older · Men · Updated Aug 21, 2026 · NCT06844383

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

  • Minnesota Oncology - Burnsville, Burnsville
  • Minnesota Oncology Hematology PA-Chaska, Chaska
  • Mercy Hospital, Coon Rapids
  • and 21 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Aug 19, 2026 · NCT04423211

Water Vapor Ablation for Prostate Cancer: Long-Term Registry

  • Minnesota Urology, Woodbury
RecruitingObservational study
All ages · Men · Updated Aug 18, 2026 · NCT07455058

FOG-001 in Locally Advanced or Metastatic Solid Tumors

  • M Health Fairview University of Minnesota Medical Center, Minneapolis
  • Mayo Clinic, Rochester
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

  • University of Minnesota Medical Center, Minneapolis
  • Mayo Clinic, Rochester
RecruitingPhase 1
Ages 18 to 100 · Men · Updated Aug 13, 2026 · NCT05519449

Adaptive Radiation Therapy (ART) Stereotactic Ablative Body Radiotherapy (SABR) for Primary Localized Prostate Cancer

  • Mayo Clinic Health System in Albert Lea, Albert Lea
  • Mayo Clinic Health System-Mankato, Mankato
  • Mayo Clinic in Rochester, Rochester
Recruiting
Ages 18 and older · Men · Updated Jul 30, 2026 · NCT06325046

MRI-guided Transurethral Urethral Ultrasound Ablation for the Treatment of Low to Intermediate Grade Prostate Cancer

  • Mayo Clinic in Rochester, Rochester
Recruiting
Ages 45 to 80 · Men · Updated Jul 22, 2026 · NCT05438563

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

  • Riverwood Healthcare Center, Aitkin
  • Essentia Health - Baxter Clinic, Baxter
  • Essentia Health Saint Joseph's Medical Center, Brainerd
  • and 18 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Jul 14, 2026 · NCT06592924

A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)

  • Mayo Clinic, Rochester
RecruitingPhase 1
Ages 18 and older · Men · Updated Jul 9, 2026 · NCT07103018

Study of ORIC-944 in Patients With Metastatic Prostate Cancer

  • Minnesota Oncology Hematology, Minneapolis
RecruitingPhase 1
Ages 18 and older · Men · Updated Jul 9, 2026 · NCT05413421

Integrated Cancer Repository for Cancer Research

  • Riverwood Healthcare Center, Aitkin
  • Essentia Health-St. Joseph's Medical Center, Brainerd
  • Essentia Health - Duluth Clinic, Duluth
  • and 2 more
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases

  • Mayo Clinic in Rochester, Rochester
RecruitingHealthy volunteers welcome
Ages 18 to 85 · All sexes · Updated Jun 10, 2026 · NCT06788886

Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer

  • Mayo Clinic Rochester, Rochester
RecruitingPhase 4
Ages 18 to 100 · Men · Updated Jun 4, 2026 · NCT05803941

A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer

  • Research Site, Rochester
RecruitingPhase 1
Ages 18 and older · Men · Updated May 12, 2026 · NCT06879041

Axelopran for Advanced Cancer in Patients Receiving Opioids

  • HealthPartners Frauenshuh Cancer Research Center, Saint Louis Park
  • HealthPartners Cancer Center at Regions Hospital, Saint Paul
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT07354919

Improvements in Dynamic Contrast-Enhanced MR Angiography and Perfusion and Non-Contrast MRI

  • Mayo Clinic in Rochester, Rochester
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Apr 17, 2026 · NCT06315595

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

  • Mayo Clinic, Rochester
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Mar 27, 2026 · NCT06395519

Screening and Staging of Benign vs Malignant Pelvic Abnormalities

  • Mayo Clinic in Rochester, Rochester
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT07407959

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.