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Sickle Cell Disease clinical trials in Massachusetts

10 studies for Sickle Cell Disease are looking for participants at sites in Massachusetts.

Cities in Massachusetts

A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

  • Boston Children's Hospital, Boston
  • Boston Medical Center, Boston
RecruitingPhase 3
Ages 12 and older · All sexes · Updated Sep 17, 2026 · NCT06612268

A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease

  • Boston Childrens Hospital, Boston
RecruitingPhase 1/2Healthy volunteers welcome
Ages 12 to 55 · All sexes · Updated Sep 9, 2026 · NCT06546670

A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

  • Local Institution - 0024, Boston
  • Boston Medical Center, Boston
RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06481306

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

  • Massachusetts General Hospital Comprehensive Hemophilia and Thrombosis Treatment Center, Boston
RecruitingObservational study
All ages · All sexes · Updated Aug 17, 2026 · NCT04398628

Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease

  • Boston Children's Hospital (MRD-HCT), Boston
  • Boston Children's Hospital (NT-DMT), Boston
RecruitingObservational study
Ages 3 to 20 · All sexes · Updated Jun 4, 2026 · NCT06941389

Promoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease

  • Boston Children's Hospital, Boston
Recruiting
Ages 8 to 25 · All sexes · Updated May 5, 2026 · NCT06555939

Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-Hemoglobinopathies

  • Boston Children's Hospital, Boston
RecruitingPhase 1
Ages 13 to 40 · All sexes · Updated Feb 3, 2026 · NCT06647979

A Long-term Follow-up Study in Patients Who Received BEAM-101

  • Boston Children's Hospital, Boston
RecruitingObservational study
Ages 14 to 37 · All sexes · Updated Jan 28, 2026 · NCT07373639

A Pilot Study on Neuroimaging in SCD: Part of The Boston Consortium to Cure Sickle Cell Disease

  • Boston Children's Hospital, Boston
RecruitingObservational study
Ages 8 to 18 · All sexes · Updated Dec 12, 2025 · NCT04166526

Study of the Role of Genetic Modifiers in Hemoglobinopathies

  • Boston Children's Hospital, Boston
RecruitingObservational study
Ages 2 and older · All sexes · Updated Mar 20, 2024 · NCT05799118

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.