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Sickle Cell Disease clinical trials in Boston, MA

10 studies for Sickle Cell Disease are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

RecruitingPhase 3
  • Boston Children's Hospital, Boston
  • Boston Medical Center, Boston
Ages 12 and older · All sexes · Updated Sep 17, 2026 · NCT06612268

A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease

RecruitingPhase 1/2Healthy volunteers welcome
  • Boston Childrens Hospital, Boston
Ages 12 to 55 · All sexes · Updated Sep 9, 2026 · NCT06546670

A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

RecruitingPhase 1/2Healthy volunteers welcome
  • Local Institution - 0024, Boston
  • Boston Medical Center, Boston
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06481306

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

RecruitingObservational study
  • Massachusetts General Hospital Comprehensive Hemophilia and Thrombosis Treatment Center, Boston
All ages · All sexes · Updated Aug 17, 2026 · NCT04398628

Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease

RecruitingObservational study
  • Boston Children's Hospital (MRD-HCT), Boston
  • Boston Children's Hospital (NT-DMT), Boston
Ages 3 to 20 · All sexes · Updated Jun 4, 2026 · NCT06941389

Promoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease

Recruiting
  • Boston Children's Hospital, Boston
Ages 8 to 25 · All sexes · Updated May 5, 2026 · NCT06555939

Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-Hemoglobinopathies

RecruitingPhase 1
  • Boston Children's Hospital, Boston
Ages 13 to 40 · All sexes · Updated Feb 3, 2026 · NCT06647979

A Long-term Follow-up Study in Patients Who Received BEAM-101

RecruitingObservational study
  • Boston Children's Hospital, Boston
Ages 14 to 37 · All sexes · Updated Jan 28, 2026 · NCT07373639

A Pilot Study on Neuroimaging in SCD: Part of The Boston Consortium to Cure Sickle Cell Disease

RecruitingObservational study
  • Boston Children's Hospital, Boston
Ages 8 to 18 · All sexes · Updated Dec 12, 2025 · NCT04166526

Study of the Role of Genetic Modifiers in Hemoglobinopathies

RecruitingObservational study
  • Boston Children's Hospital, Boston
Ages 2 and older · All sexes · Updated Mar 20, 2024 · NCT05799118

About Sickle Cell Disease

Sickle cell disease is a group of inherited disorders that affect your red blood cells. It can cause pain, anemia, and other problems. Learn about treatments.

More about Sickle Cell Disease on MedlinePlus

Sickle Cell Disease trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.