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Head and Neck Cancer clinical trials in New Haven, CT

8 studies for Head and Neck Cancer are looking for participants at sites in and around New Haven (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • Yale Cancer Center, New Haven
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
  • Yale Cancer Center, New Haven
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

RecruitingPhase 1
  • Smilow Cancer Hospital - Yale New Haven Health, New Haven
  • Yale - New Haven Hospital - Yale Cancer Center, New Haven
  • Smilow Cancer Hospital Phase 1 Unit, New Haven
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07090499

First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Yale Cancer Center, New Haven
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06657222

Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Yale University, Yale Cancer Center, New Haven
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT06993844

Skin Color Matching in Head and Neck Reconstructive Surgery

Recruiting
  • Yale New Haven Hospital, New Haven
  • Shoreline Surgery Center, Guilford · 13 mi away
Ages 18 and older · All sexes · Updated May 29, 2026 · NCT07431099

A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

RecruitingPhase 3
  • GSK Investigational Site, New Haven
Ages 18 and older · All sexes · Updated May 26, 2026 · NCT06256588

Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy System

RecruitingObservational study
  • Yale University - Cancer Center, New Haven
All ages · All sexes · Updated Aug 15, 2025 · NCT05406167

About Head and Neck Cancer

Head and neck cancer includes cancers of the mouth, nose, sinuses, salivary glands, throat, and lymph nodes. Read the different symptoms of each type.

More about Head and Neck Cancer on MedlinePlus

Head and Neck Cancer trials in other cities

Other studies in New Haven

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.